New drug vixarelimab tested for Tough-to-Treat ulcerative colitis

NCT ID NCT06693908

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This early-stage trial is testing a drug called vixarelimab in 24 people with moderate to severe ulcerative colitis who have not improved with standard treatments. The study looks at how the drug affects the gut, how it moves through the body, and whether it is safe. It is too early to know if it will help symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vixarelimab

What this could lead to

If successful, this could point toward a new treatment option for people with moderate to severe ulcerative colitis who have not responded to other therapies.

What could go wrong

This is a very early, small study (24 people) focused on safety and biological effects, not yet on symptom improvement. The drug may not work or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charité Research Organisation GmbH

    Berlin, 10117, Germany