New hope for HER2 cancers: first human trial launches

NCT ID NCT05356741

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This study tests a new drug called VIR-5818, alone or with another drug (pembrolizumab), in people with advanced HER2-positive cancers that have spread. The main goals are to check safety and find the right dose. About 645 adults with various HER2-expressing tumors will take part. The study lasts about 52 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational site number #100

    RECRUITING

    Melbourne, Victoria, 3000, Australia

  • Investigational site number #101

    RECRUITING

    Randwick, 2031, Australia

  • Investigational site number #150

    RECRUITING

    Toulouse, 31059, France

  • Investigational site number #200

    RECRUITING

    Porto, 4200-072, Portugal

  • Investigational site number #250

    RECRUITING

    Pamplona, 31008, Spain

  • Investigational site number #251

    RECRUITING

    Barcelona, 08035, Spain

  • Investigational site number #252

    RECRUITING

    Madrid, 28050, Spain

  • Investigational site number #253

    RECRUITING

    Pozuelo de Alarcón, 28223, Spain

  • Investigational site number #254

    RECRUITING

    Madrid, 28027, Spain

  • Investigational site number #255

    RECRUITING

    Barcelona, 08023, Spain

Conditions

Explore the condition pages connected to this study.