Could a cancer drug change how other medicines work? a trial investigates

NCT ID NCT07744802

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This early-stage trial is testing whether vimseltinib, an investigational drug, affects how the body processes a common blood thinner called dabigatran. Healthy male volunteers will take both drugs in a fixed order, and researchers will measure dabigatran levels in the blood to see if vimseltinib changes its absorption or breakdown. The goal is to understand potential drug interactions, which could help guide safe dosing when vimseltinib is used alongside other medications. The study lasts about three weeks and also monitors for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
vimseltinib (an investigational drug) and dabigatran (a blood thinner used as a test probe)
What this could lead to
If vimseltinib changes how the body processes other drugs, doctors may need to adjust doses when combining it with certain medications, improving safety for future patients.
What could go wrong
This is an early-stage study in a small group of healthy men, so results may not apply to patients or to other drugs. There is also a risk of unexpected side effects from the drug combination.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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