Drug trial aims to heal painful, Hard-to-Treat skin wounds

NCT ID NCT05964413

Summary

This study tested whether the drug vilobelimab could help heal painful, open skin ulcers caused by a rare condition called pyoderma gangrenosum. About 54 adults with at least one qualifying ulcer received either the drug or a placebo. The main goal was to see if the drug could lead to complete wound closure compared to the placebo.

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Contacts and locations

Locations

  • AOU Città della salute e della scienza

    Turin, Italy

  • Aby´s New Generation Research, Inc

    Hialeah, Florida, 33016, United States

  • Advanced Medical Research, PC

    Sandy Springs, Georgia, 30328, United States

  • Apex Clinical Research Center

    Mayfield Heights, Ohio, 44124, United States

  • Berge Hautklinik

    Erlangen, Bavaria, 91054, Germany

  • Brigham and Women´s Hospital

    Boston, Massachusetts, 02115, United States

  • CHU Toulouse Hospital Larrey

    Toulouse, Occitanie, 31000, France

  • CHU de Nantes - Clinique dermatologique

    Nantes, 44093, France

  • Catholic Clinic Bochum, Department of Dermatology

    Bochum, Nordrhein-Westfalia, 44791, Germany

  • Charité - Universitätsmedizin Berlin, Department of Dermatology, Venereology and Allergology, Berlin, Germany

    Berlin, Germany

  • City Clinic Przychodnia Lekarsko-Psychologiczna ul. Sliczna 13, Wroclaw, Poland

    Wroclaw, Poland

  • Cliniques Universitaires Saint-Luc

    Brussels, Belgium

  • Complejo Asistencial Universitario de Salamanca

    Salamanca, Spain

  • Department and Clinics of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin,

    Lublin, Poland

  • Department of Dermatology and Allergology, University of Szeged

    Szeged, Csongrad-Csanad, 6720, Hungary

  • Department of Dermatology, University of Debrecen

    Debrecen, Hadju-Bihar, 4032, Hungary

  • Department of Dermatology, Venerology and Oncodermatology, University of Pécs

    Pécs, Hungary

  • Dermatology/University of Miami Hospital

    Miami, Florida, 33146, United States

  • Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico SC Dermatologia

    Milan, 20122, Italy

  • ForCare Clinical Research

    Tampa, Florida, 33613, United States

  • Hospital Edouard Herriot

    Lyon, 69003, France

  • Hospital Ramón y Cajal

    Madrid, 28034, Spain

  • Hôpitaux Universitaires de Bruxelles

    Anderlecht, Belgium

  • IRCCS Policlinico di Sant'Orsola Alma Mater Studiorum - University of Bologna

    Bologna, Italy

  • Klinik und Poliklinik für Dermatologie und Allergologie

    München, Bavaria, 80337, Germany

  • Klinika Dermatologii, Chorób Przenoszonych Drogą Płciową i Immunologii Klininczej, Miejski Szpital Zespolony w Olsztynie Clinic of Dermatology,

    Olsztyn, Poland

  • Liverpool Hospital

    Sydney, Australia

  • Ohio State University Wexner Medical Cente OSU Dermatology West

    Columbus, Ohio, 43215, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Ospedale Santa Chiara

    Pisa, 56126, Italy

  • Państwowy Instytut Medyczny CSK MSWiA

    Warsaw, Poland

  • Premier Specialists

    Kogarah, NewSouth Wales, Australia

  • Saint Louis Hospital

    Paris, 75010, France

  • The Alfred Hospital, Melbourne

    Melbourne, Victoria, 3004, Australia

  • The University of Texas Health Science Center at Houston

    Bellaire, Texas, 77401, United States

  • University Hospital Basel Department of Dermatology at Universitäre Altersmedizin FELIX PLATTER

    Basel, Switzerland

  • University Hospital Leipzig AöR

    Leipzig, Germany

  • University Hospital Würzburg, Department of Dermatology

    Würzburg, Bavaria, 97080, Germany

  • University clinic Duesseldorf Department of Dermatology Heinrich-Heine-University Duesseldorf

    Düsseldorf, Germany

  • University of Central Florida College of Medicine

    Orlando, Florida, 32827, United States

  • University of Essen, Germany

    Essen, North Rhine-Westphalia, Germany

  • University of North Carolina at Chapel Hill Department of Dermatology

    Chapel Hill, North Carolina, 27516, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19194, United States

  • Universitätshautklinik Tübingen

    Tübingen, Baden Würrtemberg, 72076, Germany

  • Universitätsklinik für Dermatologie und Venerologie der MLU Halle

    Halle, Germany

  • Universitätsklinikum Frankfurt, Klinik für Dermatologie

    Frankfurt am Main, Hesse, 60590, Germany

  • Universitätsklinikum Hamburg-Eppendorf, Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP)

    Hamburg, Germany

  • Universitätsklinikum Heidelberg

    Heidelberg, Bavaria, 69120, Germany

  • Veracity Clinical Research Pty Ltd as trustee for the MLS Trust

    Brisbane, Australia

  • Wojewódzki Specjalistyczny Szpital im. Dr Wł. Biegańskiego w Łodzi; Klinika Dermatologii, Dermatologii Dziecięcej i Onkologicznej Uniwersytetu Medycznego

    Lodz, Poland

Conditions

Explore the condition pages connected to this study.