New shot aims to stop bleeding in rare blood disorder

NCT ID NCT07115004

Recruiting now Disease control Sponsor: Vega Therapeutics, Inc Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 study tests a drug called VGA039, given as a shot under the skin, to prevent bleeding in people with Von Willebrand disease. The trial will include 60 patients aged 12 to 75 who have frequent bleeding episodes. Researchers will track how well the drug reduces bleeds and check for side effects over about a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VGA039 (a drug given as a shot under the skin)
What this could lead to: If it works, this could offer a new preventive treatment to reduce bleeding episodes in people with Von Willebrand disease.
What could go wrong: This is still a phase 3 trial with only 60 participants, so results may not apply to everyone. There are risks like allergic reactions or side effects from the drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

von Willebrand disease (hereditary or acquired)

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VON WILLEBRAND DISEASE (VWD)

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Arkansas Children's Hospital
RECRUITING

Little Rock, Arkansas, 72202, United States
Charlotte Maxeke Johannesburg Academic Hospital School of Pathology Clinical Haematologist
RECRUITING

Johannesburg, 2194, South Africa
Children's Healthcare of Atlanta
RECRUITING

Atlanta, Georgia, 30329, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30308, United States
Frankfurt University Hospital (Universitätsmedizin Frankfurt)
RECRUITING

Frankfurt, 60596, Germany
Hemophilia Center of Western PA
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
K Eristavi National Center of Experimental and Clinical Surgery (ქირურგიის ეროვნული ცენტრი)
RECRUITING

Tbilisi, 0159, Georgia
Luskin Orthopaedic Institute For Children
RECRUITING

Los Angeles, California, 90007, United States
Science 37, Inc. (Virtual Clinical MetaSite)
RECRUITING

Morrisville, North Carolina, 27560, United States
UC Davis Medical Center
RECRUITING

Sacramento, California, 95817, United States
UT Southwestern Children's Hospital
RECRUITING

Dallas, Texas, 75235, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
Washington Center for Bleeding Disorders
RECRUITING

Seattle, Washington, 98101, United States

Contact Email: •••••@•••••

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