Could a targeted drug boost stem cell transplant success in AML?

NCT ID NCT06954987

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 32 times

Summary

This study tests whether adding the drug venetoclax to standard chemotherapy and a stem cell transplant can help keep acute myeloid leukemia (AML) from coming back. About 244 adults with AML in first remission will receive either venetoclax or a placebo before and after their transplant. The goal is to see if venetoclax improves event-free survival and reduces remaining cancer cells.

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