New pill combo could replace chemo for rare blood cancer

NCT ID NCT05099471

First seen Jan 04, 2026 · Last updated May 01, 2026 · Updated 20 times

Summary

This study tests whether a combination of two drugs, venetoclax and rituximab, works better than standard chemotherapy for people with untreated Waldenström's macroglobulinemia, a rare blood cancer. About 80 participants will receive either the drug combo or chemo, and researchers will measure how well the cancer responds after 12 months. The goal is to find a more effective, fixed-duration treatment that avoids the need for lifelong medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alexandra Hospital

    RECRUITING

    Athens, 115 28, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dr. Vehling-Kaiser MVZ GmbH

    RECRUITING

    Landshut, 84036, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gemeinschaftsklinikum Mittelrhein gGmbH

    RECRUITING

    Koblenz, 56073, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Haematologie und Onkologie Muenchen-Pasing MVZ GmbH

    RECRUITING

    München, 81241, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kliniken Maria Hilf GmbH Moenchengladbach

    RECRUITING

    Mönchengladbach, 41063, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum Chemnitz gGmbH

    RECRUITING

    Chemnitz, 09116, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikverbund Allgaeu gGmbH

    RECRUITING

    Kempten, 87439, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Onkologische Schwerpunktpraxis Bielefeld

    RECRUITING

    Bielefeld, 33604, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaet Muenster

    RECRUITING

    Münster, 48149, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaetsklinikum Schleswig-Holstein AöR

    NOT_YET_RECRUITING

    Kiel, 24105, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Ulm

    RECRUITING

    Ulm, 89081, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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