Promising combo for tough leukemias hits roadblock: trial ends early

NCT ID NCT03404193

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study tested a combination of two drugs, venetoclax and decitabine, in 235 people with certain blood cancers (like acute myeloid leukemia and high-risk myelodysplastic syndrome) that either came back or didn't respond to prior treatment, or in older adults who couldn't handle strong chemo. The goal was to see how many patients achieved remission. The trial was terminated early, so final results are limited.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.