Shorter treatment for tough leukemia shows promise in pilot study

NCT ID NCT05833438

First seen May 03, 2026 · Last updated May 08, 2026 · Updated 1 time

Summary

This study tests a new way of giving two drugs (venetoclax and azacitidine) to adults with acute myeloid leukemia (AML) who are too old or sick for standard chemotherapy. Instead of the usual 7 days of azacitidine, this approach uses only 5 days per cycle to reduce side effects like infections and hospital stays. The goal is to see if this shorter schedule still helps control the leukemia while being easier for patients to tolerate.

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Contacts and locations

Locations

  • Carl-Thiem-Klinikum Cottbus gGmbH

    Cottbus, 03048, Germany

  • Helios Klinikum Berlin-Buch Klinik für Hämatologie und Stammzelltransplantation

    Berlin, 13125, Germany

  • Kliniken Maria Hilf GmbH, Klinik für Hämatologie, Onkologie und Gastroenterologie

    Mönchengladbach, 41063, Germany

  • Kliniken Sindelfingen,Medizinische Klinik I

    Sindelfingen, 71065, Germany

  • Klinikum Chemnitz gGmbH Klinik für lnnere Medizin Ill

    Chemnitz, 09116, Germany

  • Klinikum rechts der lsar der TU München, Klinik und Poliklinik für lnnere Medizin Ill

    München, 81675, Germany

  • Rotkreuzklinikum München, III. Medizinische Abteilung

    München, 80364, Germany

  • Universitatsklinikum Carl Gustav Carus Dresden an der TU Dresden Medizinische Klinik und Poliklinik 1 Bereich Hamatologie

    Dresden, 01307, Germany

  • Universitätsklinikum Heidelberg, Innere Medizin V; Klinik für Hämatologie, Onkologie und Rheumatologie

    Heidelberg, 69120, Germany

  • Universitätsklinikum Leipzig, Klinik und Poliklinik für Hämatologie, Zelltherapie und Hämostaseologie

    Leipzig, Germany

Conditions

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