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Shorter treatment course may ease side effects for AML patients

NCT ID NCT05833438

Ongoing Disease control Sponsor: University of Leipzig Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new way of giving two drugs—venetoclax and azacitidine—to adults with acute myeloid leukemia (AML) who are not healthy enough for standard chemotherapy. Instead of the usual 7 days of azacitidine, this approach uses only 5 days per cycle to try to reduce infections and hospital stays. The goal is to see if the shorter regimen still works well while being easier to tolerate.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia hematologic disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOID LEUKEMIA (AML)

Contacts and locations

Locations

  • Carl-Thiem-Klinikum Cottbus gGmbH

    Cottbus, 03048, Germany

  • Helios Klinikum Berlin-Buch Klinik für Hämatologie und Stammzelltransplantation

    Berlin, 13125, Germany

  • Kliniken Maria Hilf GmbH, Klinik für Hämatologie, Onkologie und Gastroenterologie

    Mönchengladbach, 41063, Germany

  • Kliniken Sindelfingen,Medizinische Klinik I

    Sindelfingen, 71065, Germany

  • Klinikum Chemnitz gGmbH Klinik für lnnere Medizin Ill

    Chemnitz, 09116, Germany

  • Klinikum rechts der lsar der TU München, Klinik und Poliklinik für lnnere Medizin Ill

    München, 81675, Germany

  • Rotkreuzklinikum München, III. Medizinische Abteilung

    München, 80364, Germany

  • Universitatsklinikum Carl Gustav Carus Dresden an der TU Dresden Medizinische Klinik und Poliklinik 1 Bereich Hamatologie

    Dresden, 01307, Germany

  • Universitätsklinikum Heidelberg, Innere Medizin V; Klinik für Hämatologie, Onkologie und Rheumatologie

    Heidelberg, 69120, Germany

  • Universitätsklinikum Leipzig, Klinik und Poliklinik für Hämatologie, Zelltherapie und Hämostaseologie

    Leipzig, Germany

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