Glue vs. surgery: new study tests better way to fix painful leg veins

NCT ID NCT03820947

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This study tested a medical glue (VenaSeal) against standard treatments like surgery or heat for people with vein problems in their legs. About 500 adults with vein reflux took part. The main goal was to see how satisfied patients were and how well the treated veins closed up.

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Contacts and locations

Locations

  • Azienda Ospedaliera di Padova Ospendale Sant' Antonio

    Padova, 35127, Italy

  • Bedfordshire Hospitals NHS Foundation Trust

    Bedford, MK42 9DJ, United Kingdom

  • CHU Dijon Bourgogne

    Dijon, DIjon Cedex, 21079, France

  • Cambridge University Hospitals NHS Foundation Trust - Addenbrooke's Hospital

    Cambridge, CB2 0QQ, United Kingdom

  • Clinique Pasteur

    Toulouse, France

  • Clinique du Parc

    Lyon, 69006, France

  • Complejo Hospitalario Universitario Granada (Hospital Campus de la Salud)

    Granada, 18016, Spain

  • East Toronto Vascular Clinic

    Toronto, Ontario, M4L 3Y3, Canada

  • Gangnam Severance Hospital

    Seoul, South Korea

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20007-2113, United States

  • Imperial College Healthcare NHS Trust - Charing Cross Hospital

    London, W12 0HS, United Kingdom

  • Konkuk University Medical Center

    Seoul, 143-729, South Korea

  • Lake Washington Vascular

    Bellevue, Washington, 98004-4623, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • New York-Presbyterian Hospital/Weill Cornell Medical Center

    New York, New York, 10024, United States

  • OhioHealth Riverside Methodist Hospital

    Columbus, Ohio, 43214, United States

  • Orion Medical

    Houston, Texas, 77034, United States

  • Ospedale Fatebenefratelli e Oftalmico

    Milan, 20121, Italy

  • PIMA Heart and Vascular

    Tucson, Arizona, 85718, United States

  • Praxis fur Innere Medizin und Gefäβkrankheiten

    Halle, 06108, Germany

  • Rijnstate - Locatie Arnhem

    Arnhem, 6815, Netherlands

  • Sanitas Hospital Universitario La Zarzuela

    Madrid, 28023, Spain

  • Seoul National University Hospital

    Seoul, 110-744, South Korea

  • Seoul Saint Mary's Hospital

    Seoul, 137-701, South Korea

  • Sunshine Coast University Hospital

    Birtinya, 4575, Australia

  • Valley Vascular Surgical Associates

    Fresno, California, 93701, United States

  • Vascular Care Connecticut

    Darien, Connecticut, 06820, United States

  • Vascular Care Group

    Wellesley, Massachusetts, 02482, United States

  • West London Vascular and Interventional Centre

    Harrow, HA1 3UJ, United Kingdom

  • Wollongong Hospital

    Wollongong, Australia

  • Yale School of Medicine

    New Haven, Connecticut, 06510, United States

  • Yavapai Regional Medical Center

    Prescott Valley, Arizona, 86314-2255, United States

Conditions

Explore the condition pages connected to this study.