Safety check for rare disease drug shows promise

NCT ID NCT05218655

Summary

This study monitored the safety of vatiquinone in 101 patients with inherited mitochondrial diseases who had previously taken the drug in earlier trials. It tracked side effects and adverse events to understand the long-term safety profile. The goal was to gather safety data until the medication became commercially available or the development program ended.

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Contacts and locations

Locations

  • Akron Children's Hospital

    Akron, Ohio, 44308, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • CHU Montpellier - Hopital Saint-Eloi

    Montpellier, 34295, France

  • Child Neurology Center of Northwest Florida

    Gulf Breeze, Florida, 32561, United States

  • Children's Hospital of Philadelphia - CHOP

    Philadelphia, Pennsylvania, 19104, United States

  • Children's National

    Washington D.C., District of Columbia, 20010, United States

  • Chu Angers

    Angers, 49933, France

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Columbia University Medical Center - CUMC

    New York, New York, 10032, United States

  • Great Ormond Street Hospital for Children NHS Foundation Trust

    London, WC1N 3JH, United Kingdom

  • Hopital Necker-Enfants Malades

    Paris, 75015, France

  • Hospital Ruber Internacional

    Madrid, 28034, Spain

  • Hospital Sant Joan de Déu

    Barcelona, 08950, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28003, Spain

  • Hôpital de Hautepierre - Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67000, France

  • Instytut Pomnik - Centrum Zdrowia Dziecka

    Warsaw, 04-730, Poland

  • Medical University of South Carolina - MUSC

    Charleston, South Carolina, 29425, United States

  • Ospedale Pediatrico Bambino Gesù

    Roma, 00165, Italy

  • PTC Clinical Site

    Japanese City, Japan

  • Seattle Children Hospital

    Seattle, Washington, 98105, United States

  • Stanford University

    Stanford, California, 94305, United States

  • The Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • UT Health The University of Texas

    Houston, Texas, 77030, United States

  • University of California, San Diego Altman Clinical and Translational Research Institute

    La Jolla, California, 92037, United States

  • Yale Medicine

    New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.