Which dose works best? study tests two strengths of thyroid cancer drug

NCT ID NCT01496313

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 28 times

Summary

This study tested two daily doses (150 mg vs 300 mg) of the drug vandetanib in 81 adults with advanced medullary thyroid cancer that had spread or caused symptoms. The goal was to see which dose better shrinks tumors and to compare side effects. Participants took the drug by mouth and were monitored for tumor response using standard criteria.

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Contacts and locations

Locations

  • Investigational Site Number : 1901

    Prague, 15006, Czechia

  • Investigational Site Number : 1903

    Olomouc, 77900, Czechia

  • Investigational Site Number : 5703

    Gliwice, 44-101, Poland

  • Investigational Site Number : 5704

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • Research Site

    Houston, Texas, United States

  • Research Site

    Olomouc, Czechia

  • Research Site

    Prague, Czechia

  • Research Site

    Bangalore Karnataka, India

  • Research Site

    Vellore, India

  • Research Site

    Beersheba, Israel

  • Research Site

    Haifa, Israel

  • Research Site

    Jerusalem, Israel

  • Research Site

    Petah Tikva, Israel

  • Research Site

    Catania, Italy

  • Research Site

    Milan, Italy

  • Research Site

    Palermo, Italy

  • Research Site

    Pisa, Italy

  • Research Site

    Roma, Italy

  • Research Site

    Siena, Italy

  • Research Site

    Torino, Italy

  • Research Site

    Groningen, Netherlands

  • Research Site

    Leiden, Netherlands

  • Research Site

    Gliwice, Poland

  • Research Site

    Warsaw, Poland

  • Research Site

    Zgierz, Poland

  • Research Site

    Saint Petersburg, Russia

  • Research Site

    Cardiff, United Kingdom

  • Research Site

    Greater London, United Kingdom

  • Research Site

    London, United Kingdom

  • Research Site

    Tyne & Wear, United Kingdom

Conditions

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