New eye injection trial aims to restore vision damaged by inflammation

NCT ID NCT05642312

Summary

This study tested whether a new drug called vamikibart, given as an injection into the eye, could safely reduce swelling and improve vision in people with uveitic macular edema. It involved 245 participants who received either the real injection or a sham (pretend) procedure. The main goal was to see if the drug helped people read more letters on an eye chart 16 weeks after treatment.

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Contacts and locations

Locations

  • AIBILI - Association for Innovation and Biomedical Research on Light

    Coimbra, 3000-548, Portugal

  • ASL 4 SSR Ospedale Santa Maria di Montallegro

    Rapallo, Liguria, 16035, Italy

  • AUSL ? IRCCS Santa Maria Nuova

    Reggio Emilia, Emilia-Romagna, 42100, Italy

  • Ajou University Medical Center

    Gyeonggi-do, 16499, South Korea

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Asst Fatebenefratelli Sacco

    Milan, Lombardy, 20157, Italy

  • Assuta Hashalom Medical Center

    Tel Aviv, 6789140, Israel

  • Austin Clinical Research LLC

    Austin, Texas, 78750, United States

  • Beijing Tongren Hospital

    Beijing, 100730, China

  • Bradford Royal Infirmary

    Bradford, BD9 6RJ, United Kingdom

  • Bristol Eye Hospital

    Bristol, BS1 2LX, United Kingdom

  • CEMAPE - Centro Médico

    São Paulo, São Paulo, 04084-002, Brazil

  • CHU de Quebec-Universite Laval

    Québec, G1S 4L8, Canada

  • Chang Gung Medical Foundation - Linkou

    Taoyuan District, 333, Taiwan

  • Colorado Retina Associates, PC

    Lakewood, Colorado, 80228, United States

  • Cumberland Valley Retina PC

    Hagerstown, Maryland, 21740, United States

  • Envision Ocular, LLC

    Bloomfield, New Jersey, 07003, United States

  • Erie Retina Research

    Erie, Pennsylvania, 16507-1429, United States

  • Eye Hospital, Wenzhou Medical University

    Wenzhou, 325027, China

  • Fiocruz - Fundação Oswaldo Cruz

    Rio de Janeiro, 21040-360, Brazil

  • Gabinet Okulistyczny Prof Edward Wylegala

    Katowice, 40-594, Poland

  • Gloucestershire Hospitals NHS Foundation Trust

    Gloucestershire, GL1 3NN, United Kingdom

  • Hadassah MC

    Jerusalem, 9112001, Israel

  • Het Oogziekenhuis Rotterdam

    Rotterdam, 3011 BH, Netherlands

  • Hospital de Santa Maria

    Lisbon, 1649-035, Portugal

  • Hospital de la Ceguera APEC

    Mexico City, Mexico CITY (federal District), 04030, Mexico

  • Hôpital Maisonneuve - Rosemont

    Montreal, Quebec, H1T 2M4, Canada

  • Instituto de Oftalmologia Dr. Gama Pinto

    Lisbon, 1169-019, Portugal

  • Irccs Ospedale San Raffaele

    Milan, Lombardy, 20132, Italy

  • James Cook Hospital

    Middlesbrough, TS4 3BW, United Kingdom

  • Kaiser Permanente Southern California

    Los Angeles, California, 90027, United States

  • Kaplan Medical Center

    Rehovot, 7660101, Israel

  • Kensington Vision and Research Centre

    Toronto, Ontario, M5T 3A9, Canada

  • Kepler Universitätskliniken GmbH - Med Campus III

    Linz, 4021, Austria

  • Kim's Eye Hospital

    Seoul, 07301, South Korea

  • LKH-Univ.Klinikum Graz

    Graz, 8036, Austria

  • Mackay Memorial Hospital

    Taipei, Taiwan

  • Medizinische Universitat Wien

    Vienna, 1090, Austria

  • Meir Medical Center

    Kfar Saba, 4428164, Israel

  • OFTALMIKA Sp. z o.o

    Bydgoszcz, 85-631, Poland

  • Oregon Health & Science Uni

    Portland, Oregon, 97239, United States

  • Palmetto Retina Center

    West Columbia, South Carolina, 29169, United States

  • Peking Union Medical College Hospital

    Beijing, 100032, China

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Queen Elizabeth Hospital

    Birmingham, B15 2TH, United Kingdom

  • Rabin MC

    Petah Tikva, 4941492, Israel

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Ren Min Hospital Affiliated Wu Han University

    Wuhan, 430060, China

  • Retina Clinic

    São Paulo, São Paulo, 01427-002, Brazil

  • Retina Vitreous Associates of Florida

    St. Petersburg, Florida, 33711-1141, United States

  • Royal Liverpool University Hospital

    Liverpool, L7 8XP, United Kingdom

  • SP ZOZ Szpital Uniwersytecki w Krakowie Oddzia? Kliniczny Okulistyki i Onkologii Okulistycznej

    Krakow, 31-501, Poland

  • SPEKTRUM Osrodek Okulistyki Klinicznej

    Wroclaw, 53-334, Poland

  • SPSK nr 1 w Lublinie

    Lublin, 20-079, Poland

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Second Affiliated Hospital Zhejiang University College of Medicine

    Hangzhou, China

  • Seoul National University Bundang Hospital

    Seongnam-si, 13605, South Korea

  • Seoul St Mary's Hospital

    Seoul, 06591, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • Shanghai First People's Hospital

    Shanghai, 200080, China

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Tel Aviv Sourasky MC

    Tel Aviv, 6423906, Israel

  • Tennessee Retina PC

    Nashville, Tennessee, 37203, United States

  • Texas Retina Associates

    Dallas, Texas, 75231, United States

  • The First Affiliated Hospital, Chongqing Medical University

    Chongqing, 400016, China

  • The Ohio State University Investigational Drug Services

    Columbus, Ohio, 43212, United States

  • The Second Hospital of Jilin University

    Changchun, 130041, China

  • Tianjin Medical University Eye Hospital

    Tianjin, 300070, China

  • Truhlsen Eye Institute

    Omaha, Nebraska, 68106-5540, United States

  • Universidade Federal de Sao Paulo - UNIFESPX

    São Paulo, São Paulo, 04023-062, Brazil

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • VitreoRetinal Surgery, PLLC.

    Minneapolis, Minnesota, 55435, United States

  • Wake Forest Baptist Health Eye Centre

    Winston-Salem, North Carolina, 27157, United States

  • Western Eye Hospital

    London, NW1 5QH, United Kingdom

  • Yeungnam University Medical Center

    Daegu, 42415, South Korea

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    Guangzhou, 510060, China

Conditions

Explore the condition pages connected to this study.