New eye injection trial aims to restore vision damaged by inflammation
NCT ID NCT05642312
Summary
This study tested whether a new drug called vamikibart, given as an injection into the eye, could safely reduce swelling and improve vision in people with uveitic macular edema. It involved 245 participants who received either the real injection or a sham (pretend) procedure. The main goal was to see if the drug helped people read more letters on an eye chart 16 weeks after treatment.
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Contacts and locations
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Locations
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AIBILI - Association for Innovation and Biomedical Research on Light
Coimbra, 3000-548, Portugal
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ASL 4 SSR Ospedale Santa Maria di Montallegro
Rapallo, Liguria, 16035, Italy
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AUSL ? IRCCS Santa Maria Nuova
Reggio Emilia, Emilia-Romagna, 42100, Italy
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Ajou University Medical Center
Gyeonggi-do, 16499, South Korea
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Asan Medical Center
Seoul, 05505, South Korea
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Asst Fatebenefratelli Sacco
Milan, Lombardy, 20157, Italy
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Assuta Hashalom Medical Center
Tel Aviv, 6789140, Israel
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Austin Clinical Research LLC
Austin, Texas, 78750, United States
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Beijing Tongren Hospital
Beijing, 100730, China
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Bradford Royal Infirmary
Bradford, BD9 6RJ, United Kingdom
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Bristol Eye Hospital
Bristol, BS1 2LX, United Kingdom
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CEMAPE - Centro Médico
São Paulo, São Paulo, 04084-002, Brazil
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CHU de Quebec-Universite Laval
Québec, G1S 4L8, Canada
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Chang Gung Medical Foundation - Linkou
Taoyuan District, 333, Taiwan
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Colorado Retina Associates, PC
Lakewood, Colorado, 80228, United States
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Cumberland Valley Retina PC
Hagerstown, Maryland, 21740, United States
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Envision Ocular, LLC
Bloomfield, New Jersey, 07003, United States
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Erie Retina Research
Erie, Pennsylvania, 16507-1429, United States
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Eye Hospital, Wenzhou Medical University
Wenzhou, 325027, China
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Fiocruz - Fundação Oswaldo Cruz
Rio de Janeiro, 21040-360, Brazil
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Gabinet Okulistyczny Prof Edward Wylegala
Katowice, 40-594, Poland
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Gloucestershire Hospitals NHS Foundation Trust
Gloucestershire, GL1 3NN, United Kingdom
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Hadassah MC
Jerusalem, 9112001, Israel
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Het Oogziekenhuis Rotterdam
Rotterdam, 3011 BH, Netherlands
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Hospital de Santa Maria
Lisbon, 1649-035, Portugal
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Hospital de la Ceguera APEC
Mexico City, Mexico CITY (federal District), 04030, Mexico
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Hôpital Maisonneuve - Rosemont
Montreal, Quebec, H1T 2M4, Canada
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Instituto de Oftalmologia Dr. Gama Pinto
Lisbon, 1169-019, Portugal
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Irccs Ospedale San Raffaele
Milan, Lombardy, 20132, Italy
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James Cook Hospital
Middlesbrough, TS4 3BW, United Kingdom
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Kaiser Permanente Southern California
Los Angeles, California, 90027, United States
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Kaplan Medical Center
Rehovot, 7660101, Israel
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Kensington Vision and Research Centre
Toronto, Ontario, M5T 3A9, Canada
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Kepler Universitätskliniken GmbH - Med Campus III
Linz, 4021, Austria
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Kim's Eye Hospital
Seoul, 07301, South Korea
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LKH-Univ.Klinikum Graz
Graz, 8036, Austria
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Mackay Memorial Hospital
Taipei, Taiwan
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Medizinische Universitat Wien
Vienna, 1090, Austria
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Meir Medical Center
Kfar Saba, 4428164, Israel
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OFTALMIKA Sp. z o.o
Bydgoszcz, 85-631, Poland
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Oregon Health & Science Uni
Portland, Oregon, 97239, United States
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Palmetto Retina Center
West Columbia, South Carolina, 29169, United States
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Peking Union Medical College Hospital
Beijing, 100032, China
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Pusan National University Hospital
Busan, 49241, South Korea
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Queen Elizabeth Hospital
Birmingham, B15 2TH, United Kingdom
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Rabin MC
Petah Tikva, 4941492, Israel
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Rambam Medical Center
Haifa, 3109601, Israel
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Ren Min Hospital Affiliated Wu Han University
Wuhan, 430060, China
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Retina Clinic
São Paulo, São Paulo, 01427-002, Brazil
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Retina Vitreous Associates of Florida
St. Petersburg, Florida, 33711-1141, United States
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Royal Liverpool University Hospital
Liverpool, L7 8XP, United Kingdom
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SP ZOZ Szpital Uniwersytecki w Krakowie Oddzia? Kliniczny Okulistyki i Onkologii Okulistycznej
Krakow, 31-501, Poland
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SPEKTRUM Osrodek Okulistyki Klinicznej
Wroclaw, 53-334, Poland
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SPSK nr 1 w Lublinie
Lublin, 20-079, Poland
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Samsung Medical Center
Seoul, 06351, South Korea
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Second Affiliated Hospital Zhejiang University College of Medicine
Hangzhou, China
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Seoul National University Bundang Hospital
Seongnam-si, 13605, South Korea
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Seoul St Mary's Hospital
Seoul, 06591, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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Shanghai First People's Hospital
Shanghai, 200080, China
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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Tel Aviv Sourasky MC
Tel Aviv, 6423906, Israel
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Tennessee Retina PC
Nashville, Tennessee, 37203, United States
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Texas Retina Associates
Dallas, Texas, 75231, United States
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The First Affiliated Hospital, Chongqing Medical University
Chongqing, 400016, China
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The Ohio State University Investigational Drug Services
Columbus, Ohio, 43212, United States
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The Second Hospital of Jilin University
Changchun, 130041, China
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Tianjin Medical University Eye Hospital
Tianjin, 300070, China
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Truhlsen Eye Institute
Omaha, Nebraska, 68106-5540, United States
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Universidade Federal de Sao Paulo - UNIFESPX
São Paulo, São Paulo, 04023-062, Brazil
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Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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VitreoRetinal Surgery, PLLC.
Minneapolis, Minnesota, 55435, United States
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Wake Forest Baptist Health Eye Centre
Winston-Salem, North Carolina, 27157, United States
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Western Eye Hospital
London, NW1 5QH, United Kingdom
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Yeungnam University Medical Center
Daegu, 42415, South Korea
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Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, 510060, China
Conditions
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