Diabetes drug could boost surgery for C-Section scar problems
NCT ID NCT05205317
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares vaginal repair surgery alone versus surgery plus metformin for women with a cesarean scar defect that causes prolonged menstrual bleeding. About 100 women under 40 with a thin scar muscle layer will be randomly assigned to one of the two groups. The goal is to see if metformin, an anti-aging drug, helps the scar heal better and shortens periods.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin (a diabetes drug) and vaginal repair surgery
What this could lead to
If it works, this could offer a more effective treatment for cesarean scar defect, reducing heavy periods and improving quality of life.
What could go wrong
This is a small, early-stage trial with only 100 participants. Metformin may not improve outcomes, and surgery carries typical risks like infection or scarring.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEFECT are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 200092, China
Contact Phone: •••-•••-•••• Email: •••••@•••••