Diabetes drug could boost surgery for C-Section scar problems
NCT ID NCT05205317
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares vaginal repair surgery alone versus surgery plus metformin for women with a cesarean scar defect that causes prolonged menstrual bleeding. About 100 women under 40 with a thin scar muscle layer will be randomly assigned to one of the two groups. The goal is to see if metformin, an anti-aging drug, helps the scar heal better and shortens periods.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metformin (a diabetes drug) and vaginal repair surgery
- What this could lead to
- If it works, this could offer a more effective treatment for cesarean scar defect, reducing heavy periods and improving quality of life.
- What could go wrong
- This is a small, early-stage trial with only 100 participants. Metformin may not improve outcomes, and surgery carries typical risks like infection or scarring.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 200092, China