New pill for bladder pain shows promise in early trial

NCT ID NCT06285214

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a drug called V117957 in 47 women with interstitial cystitis, a condition causing bladder pain and discomfort. Participants took either the drug or a placebo at bedtime to see if it safely reduced pain. The trial is now complete, and results will help decide if larger studies are warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

V117957

What this could lead to

If it works, this could point toward a new treatment option for bladder pain in interstitial cystitis.

What could go wrong

This is an early Phase 1 trial with only 47 participants, so results may not apply to everyone. The drug may not prove effective or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial cystitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Accel Research Site - Neurostudies

    Decatur, Georgia, 30033, United States

  • Accel Research Sites

    DeLand, Florida, 32720, United States

  • AccuMed Research Associates

    Garden City, New York, 11530, United States

  • Adult & Pediatric Urology P.C.

    Omaha, Nebraska, 68114, United States

  • Applied Research Center of Arkansas

    Little Rock, Arkansas, 72212, United States

  • Bay State Clinical Trials, Inc.

    Watertown, Massachusetts, 02472, United States

  • Boston Clinical Trials

    Boston, Massachusetts, 02131, United States

  • CentraCare - Urology Clinic

    Sartell, Minnesota, 56377, United States

  • Chesapeake Urology Research Associates

    Owings Mills, Maryland, 21117, United States

  • Hope Clinical Research, LLC

    Los Angeles, California, 91303, United States

  • Investigational Site

    Escondido, California, 92025, United States

  • Manhattan Medical Research Practice

    New York, New York, 10016, United States

  • MetroHealth System

    Cleveland, Ohio, 44109, United States

  • MidLantic Urology

    Bala-Cynwyd, Pennsylvania, 19004, United States

  • Ochsner Louisiana State University Health Shreveport - Regional University

    Shreveport, Louisiana, 71106, United States

  • Otrimed Clinical Research

    Edgewood, Kentucky, 41017, United States

  • Providea Health Partners LLC

    Evergreen Park, Illinois, 60805, United States

  • Revive Research Institute, Inc

    Dearborn Heights, Michigan, 48127, United States

  • Southern Clinical Research Associates

    Metairie, Louisiana, 70001, United States

  • Tri Valley Urology Medical Group

    Murrieta, California, 92562, United States

  • Unified Women's Clinical Research-Lyndhurst Clinical Research

    Winston-Salem, North Carolina, 27103, United States

  • Urological Associates of Southern Arizona

    Tucson, Arizona, 85715, United States

  • Urology Centers of Alabama, PC

    Homewood, Alabama, 35209, United States

  • Urology Group of Southern California

    Los Angeles, California, 90017, United States