New vaccine aims to shield HIV patients from pneumonia

NCT ID NCT05393037

First seen Feb 05, 2026 · Last updated May 23, 2026 · Updated 15 times

Summary

This study tested a new vaccine called V116 in 313 adults living with HIV to see if it can safely prevent pneumococcal disease (a serious lung infection). Participants received either the new vaccine or an existing one, and researchers monitored side effects and immune responses. The goal is to offer better protection for people with HIV, who are at higher risk for this disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Be Part Yoluntu Centre ( Site 0902)

    Paarl, Western Cape, 7646, South Africa

  • CHU Saint-Pierre ( Site 0500)

    Brussels, Bruxelles-Capitale, Region de, 1000, Belgium

  • Faculty of Medicine Siriraj Hospital-Preventive and social ( Site 1100)

    Bangkok, Bangkok, 10700, Thailand

  • Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 0601)

    Paris, 75014, France

  • Hospital hernan henriquez aravena de temuco-Unidad de Investigación Clínica ( Site 0101)

    Temuco, Araucania, 4781151, Chile

  • Hôpital Saint-Louis ( Site 0600)

    Paris, Île-de-France Region, 75010, France

  • Insituut voor tropische Geneeskunde ( Site 0501)

    Antwerp, 2000, Belgium

  • Josha Research ( Site 0900)

    Bloemfontein, Free State, 9300, South Africa

  • KC CARE Health Center ( Site 0013)

    Kansas City, Missouri, 64111, United States

  • Midway Immunology and Research Center ( Site 0003)

    Ft. Pierce, Florida, 34982, United States

  • North Texas Infectious Diseases Consultants, P.A ( Site 0001)

    Dallas, Texas, 75246, United States

  • Orlando Immunology Center ( Site 0004)

    Orlando, Florida, 32803, United States

  • Perinatal HIV Research Unit (PHRU)-Adult Treatment and Research ( Site 0906)

    Johannesburg, Gauteng, 1862, South Africa

  • Pueblo Family Physicians ( Site 0014)

    Phoenix, Arizona, 85015, United States

  • Research Institute for Health Sciences-Research Institute for Health Sciences Building 1 ( Site 1101

    Chiang Mai, 50200, Thailand

  • Right To Care Research - Esizayo ( Site 0904)

    Johannesburg, Gauteng, 2087, South Africa

  • Texas Center for Infectious Disease Associates ( Site 0011)

    Fort Worth, Texas, 76104, United States

  • Universidad San Sebastian - Providencia ( Site 0111)

    Providencia, Region M. de Santiago, 7500000, Chile

  • Universidad de Chile - Hospital Clínico Universidad de Chile ( Site 0107)

    Santiago, Region M. de Santiago, 8380420, Chile

  • Whitman-Walker Institute ( Site 0009)

    Washington D.C., District of Columbia, 20005, United States

Conditions

Explore the condition pages connected to this study.