New vaccine shows promise in preventing childhood ear infections

NCT ID NCT04193215

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 24 times

Summary

This study tested a new vaccine called V114 to see if it could prevent ear infections caused by certain bacteria in babies. Over 7,000 healthy infants around 2 months old took part. Researchers compared how many babies got vaccine-type ear infections and monitored for serious side effects.

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Contacts and locations

Locations

  • Bamrasnaradura Infectious Disease Institute ( Site 0011)

    Nonthaburi, 11000, Thailand

  • Bhumibol Adulyadej Hospital ( Site 0013)

    Sai Mai, Bangkok, 10220, Thailand

  • Chiang Rai Prachanuchro Hospital-Pediatrics ( Site 0015)

    Chiang Rai, 57000, Thailand

  • Chulalongkorn University ( Site 0008)

    Bangkok, Bangkok, 10330, Thailand

  • Faculty of Medicine Thammasat Univ. ( Site 0007)

    Khong Luang, Changwat Pathum Thani, 12120, Thailand

  • Maharaj Nakorn Chiang Mai Hospital ( Site 0001)

    Chiang Mai, 50200, Thailand

  • Panyananthaphikkhu Chonprathan Medical Center ( Site 0014)

    Pak Kret, Changwat Nonthaburi, 11120, Thailand

  • Phramongkutklao Hospital ( Site 0003)

    Bangkok, Bangkok, 10400, Thailand

  • Prince of Songkla University Faculty of Medicine ( Site 0005)

    Hat Yai, Changwat Songkhla, 90110, Thailand

  • Ramathibodi Hospital, Mahidol University ( Site 0009)

    Rajthevee, Bangkok, 10400, Thailand

  • Sappasit Prasong Hosptial-Pediatric ( Site 0016)

    Ubon Ratchathani, 34000, Thailand

  • Siriraj Hospital ( Site 0004)

    Bangkok, Bangkok, 10700, Thailand

  • Srinagarind Hospital ( Site 0002)

    Khon Kaen, 40002, Thailand

Conditions

Explore the condition pages connected to this study.