New drug UX016 targets rare muscle disease

NCT ID NCT07511556

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests UX016, a drug designed to help people with GNE myopathy, a rare genetic muscle-weakening disease. Researchers will give the drug or a placebo to 24 adults to see if it is safe and improves muscle strength. The study is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UX016 (Sialic Acid-C16 prodrug)

What this could lead to

If successful, UX016 could become the first treatment to slow or improve muscle weakness in people with GNE myopathy.

What could go wrong

This is a very early, small trial (24 people) testing safety and effectiveness. It may not show benefit, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Distal myopathy, Nonaka type GNE myopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Trial Site

    Orange, California, 92868, United States

  • Clinical Trial Site

    Iselin, New Jersey, 08830, United States