New drug combo aims to fight stomach cancer

NCT ID NCT06841679

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new chemotherapy drug called utidelone, given as a capsule, together with standard chemotherapy for people with advanced stomach or gastroesophageal junction cancer that has not been treated before. The trial will enroll about 778 participants across multiple countries. Researchers want to see if the combination helps people live longer and shrinks tumors, while also checking for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Utidelone capsule (a chemotherapy drug) combined with standard chemotherapy (capecitabine, oxaliplatin, or FOLFOX)

What this could lead to

If successful, this could provide a new first-line treatment option for advanced stomach cancer, potentially improving survival and tumor shrinkage.

What could go wrong

This is an early-to-mid stage trial (phase 2/3) and the drug combination may cause significant side effects. It may not prove more effective than current standard treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastroesophageal adenocarcinoma gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AnYang Tumor Hospital

    RECRUITING

    Anyang, China

    Contact

  • Bioresearch Partner

    NOT_YET_RECRUITING

    Hialeah, Florida, 33013, United States

    Contact

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, China

    Contact

  • Jinan Municipal Central Hospital

    RECRUITING

    Jinan, China

    Contact

  • Liaoning Cancer Hospital

    RECRUITING

    Shenyang, China

    Contact

  • Shandong First Medical University Affiliated Tumor Hospital

    RECRUITING

    Jinan, China

    Contact

  • Shanxi Cancer Hospital

    NOT_YET_RECRUITING

    Taiyuan, China

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, China

    Contact

  • Tianjin Medical University Cancer Institute & Hospital

    NOT_YET_RECRUITING

    Tianjin, China

    Contact

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, China

    Contact