New combo test slashes unnecessary antibiotic use in ER lung infection patients

NCT ID NCT05463406

First seen Apr 28, 2026 · Last updated May 23, 2026 · Updated 5 times

Summary

This study tested a new approach in Swiss emergency rooms to reduce unnecessary antibiotic use for lower respiratory tract infections. Doctors used a clinical score, a lung ultrasound, and a blood test called procalcitonin to decide whether antibiotics were needed. The goal was to see if this strategy could safely lower antibiotic prescriptions compared to usual care. Over 1,400 adults participated, and the study tracked both antibiotic use and patient safety outcomes.

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Contacts and locations

Locations

  • Cantonal Hospital of St. Gallen

    Sankt Gallen, Canton of St. Gallen, 9007, Switzerland

  • Cantonal hospital of Baden

    Baden, Canton of Aargau, 5404, Switzerland

  • Centre hospitalier universitaire vaudois (CHUV)

    Lausanne, Canton of Vaud, 1011, Switzerland

  • Hôpital Intercantonal de la Broye

    Payerne, Canton of Vaud, 1530, Switzerland

  • Hôpital Riviera-Chablais

    Rennaz, Canton of Vaud, 1847, Switzerland

  • Kantonsspital Baselland

    Liestal, Canton of Basel-City, 4410, Switzerland

  • Luzerner Kantonsspital

    Lucerne, Canton of Lucerne, 6000, Switzerland

  • Réseau Hospitalier Neuchâtelois

    Neuchâtel, Canton of Neuchâtel, 2000, Switzerland

  • University Hospital of Basel

    Basel, Canton of Basel-City, 4031, Switzerland

Conditions

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