Urine protein may spot kidney transplant trouble before standard tests

NCT ID NCT07176806

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 32 times

Summary

This study looks at whether a protein called Dickkopf 3 (DKK3) in urine can detect kidney transplant problems earlier than current blood tests. Researchers will collect urine samples from 258 kidney transplant recipients over 12 months and compare the new test with standard measures like creatinine and eGFR. If successful, this could help doctors intervene sooner to protect the transplanted kidney.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guy's and St Thomas' Hospital NHS foundation Trust

    London, SE1 7EH, United Kingdom

Conditions

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