Off-the-Shelf cell therapy takes on tough leukemia

NCT ID NCT07491263

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new 'universal' cell therapy (QH103) for people with a hard-to-treat type of leukemia (B-ALL) that has come back or not responded to standard treatment. The therapy uses donor immune cells engineered to target cancer cells, given after chemotherapy to prepare the body. Only 6 participants will be enrolled to check safety and tolerability first.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QH103 Cell Injection (CD19 CAR-γδ T cells) with cyclophosphamide and fludarabine

What this could lead to

If it works, this could point toward a more accessible 'off-the-shelf' cell therapy for hard-to-treat leukemia, reducing the need for patient-specific treatments.

What could go wrong

This is a very early Phase 1 trial with only 6 people, focused on safety, not effectiveness. The therapy may not work, and there are risks like severe immune reactions or organ damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The first affiliated hospital of fujian medical university

    Fuzhou, Fujian, 350005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••