New filler takes on restylane for wrinkle correction
NCT ID NCT07150273
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new dermal filler called UNIVELO Sub-Q against the well-known Restylane Sub-Q for temporarily smoothing deep smile lines (nasolabial folds). 65 adults with moderate to severe wrinkles received both fillers on opposite sides of their face. Researchers measured wrinkle severity and aesthetic improvement over 48 weeks to see if the new filler works as well as the existing one.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
UNIVELO Sub-Q (dermal filler injection)
What this could lead to
If it works, this could offer a new option for temporarily reducing deep smile lines, similar to existing fillers.
What could go wrong
This is a small, single-center study comparing two fillers. Results may not apply to everyone, and effects are temporary. Risks include swelling, bruising, or uneven results.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.