Scientists hunt for genetic clues in rare lymphoma that turns deadly
NCT ID NCT06712459
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is looking at a rare and aggressive form of lymphoma called transformed splenic marginal zone lymphoma (t-SMZL). The goal is to understand the genetic changes that happen when the disease transforms and becomes harder to treat. Researchers will analyze tumor samples from 100 adults to find patterns that could lead to better treatments in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward more specific and effective treatments for this aggressive lymphoma.
- What could go wrong
- This is an observational study, not a treatment trial. It aims to gather knowledge, not test a therapy, so direct patient benefit is not guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University
NOT_YET_RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
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Fondazione IRCCS Policlinico San Matteo
RECRUITINGPavia, 27100, Italy
Contact Email: •••••@•••••
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, 08036, Spain
Contact Email: •••••@•••••
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Hôpital Saint Louis
RECRUITINGParis, 75475, France
Contact Email: •••••@•••••
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Oncology Institute of Southern Switzerland
NOT_YET_RECRUITINGBellinzona, 6500, Switzerland
Contact Email: •••••@•••••
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University Hospitals Dorset
NOT_YET_RECRUITINGBournemouth, BH7 7DW, United Kingdom
Contact Email: •••••@•••••
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Universitz Hospitals Leuven
NOT_YET_RECRUITINGLeuven, 3000, Belgium
Contact Email: •••••@•••••
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