New study probes exercise crash in chronic fatigue patients

NCT ID NCT04740736

First seen Jan 05, 2026 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study looked at how the heart and lungs work in people with Chronic Fatigue Syndrome (ME/CFS) and how that relates to post-exertional malaise (PEM), a severe worsening of symptoms after activity. About 80 participants completed two days of maximal exercise tests, and those with low blood volume received either a saline infusion or a sham treatment before the second test. The goal was to better understand the body's response to exercise in ME/CFS.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

Conditions

Explore the condition pages connected to this study.