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MRI roadmap may sharpen accuracy of muscle injections

NCT ID NCT06091059

Knowledge-focused Sponsor: Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study explores whether combining MRI images with real-time ultrasound can make muscle injections more accurate. Sometimes ultrasound alone is hard to interpret, especially when muscles are stiff. The MRI acts like a roadmap to help guide the needle. Researchers are comparing this new method to standard ultrasound guidance in adults who need Botox injections for muscle stiffness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Botox (onabotulinumtoxinA) injected into muscles
What this could lead to
If successful, this approach could make muscle injections more precise, potentially improving relief for people with muscle stiffness or spasticity.
What could go wrong
This is a very small, early study with only 7 participants. The new technique may not prove more accurate than standard ultrasound guidance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

7 people

The number who actually took part.

Started

Apr 2024

Finished

Jun 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

\- All adult patients with capacity and requiring an ultrasound guided Botox injection in the Radiology Department will be invited to take part in the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adult patients with capacity and requiring an ultrasound guided Botox injection in the Radiology Department will be invited to take part in the study. Exclusion Criteria: * Children. People who cannot consent. Patients with contra-indications to MRI scanning

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ultrasound diagnostic, mri fusion

Contacts and locations

Locations

  • The Robert Jones and Agnes hunt

    Oswestry, Shropshire, SY10 7AG, United Kingdom