Can running 100km change your Eye's blood vessels?
NCT ID NCT07748936
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This pilot study looks at whether running an ultra-trail race—a very long, intense endurance event—causes temporary changes in the tiny blood vessels at the back of the eye. Researchers will use a non-invasive imaging technique called OCT angiography to measure blood flow in the retina and choroid of ultra-trail runners before and shortly after the race. They will compare these measurements to a control group of active people who do not run the race. The goal is to understand how extreme physical exertion affects eye circulation and whether retinal imaging could serve as a window into overall cardiovascular health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Retinal imaging (OCT angiography and retinophotography) before and after an ultra-trail race
- What this could lead to
- If this works, it could show that simple eye scans can reveal how extreme exercise stresses the body's blood vessels, potentially aiding cardiovascular research and prevention.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. Changes in eye blood flow after a race might be temporary and not reflect long-term health.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu Dijon Bourgogne
Dijon, 21000, France
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