Could a common drug alter muscle relaxants in surgery?
NCT ID NCT05716256
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This trial investigates whether ulinastatin, a drug sometimes used during surgery, affects the action of two common muscle relaxants (rocuronium and cisatracurium). The study involves 120 adults aged 25 to 60 undergoing pancreatic surgery. Researchers measure how quickly the muscle relaxants take effect and how long they last, comparing those who receive ulinastatin to those who get a placebo. The goal is to improve anesthesia care by understanding potential drug interactions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ulinastatin
- What this could lead to
- If ulinastatin changes how muscle relaxants work, it could help anesthesiologists adjust doses for safer surgeries.
- What could go wrong
- This is a small, early-stage study in one type of surgery. Results may not apply to other patients or procedures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China