Major trial tests potential Game-Changer for debilitating bowel disease

NCT ID NCT06588855

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether a new drug called Afimkibart can help people with moderate to severe ulcerative colitis. Researchers will compare the drug against a placebo in 350 participants to see if it reduces symptoms and improves gut health over 12 weeks. The goal is to control the disease and improve quality of life for those who haven't found relief from other treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"City Clinic UMHAC" EOOD
RECRUITING

Sofia, 1407, Bulgaria
AIG Hospitals
RECRUITING

Gachibowli, Telangana, 500032, India
AZ Oostende
RECRUITING

Ostend, 8400, Belgium
AZORG Campus Aalst-Moorselbaan
RECRUITING

Aalst, 9300, Belgium
Accout Center s.r.o.
RECRUITING

Šahy, 936 01, Slovakia
Advanced Medical Research Center
RECRUITING

Port Orange, Florida, 32127, United States
Allied Biomedical Research Institute
RECRUITING

Miami, Florida, 33155, United States
Allied Gastrointestinal Associates, PA
RECRUITING

Flowood, Mississippi, 39232, United States
Ambert Medical Research
RECRUITING

Miami, Florida, 33176, United States
Amel Med LLC
RECRUITING

Georgetown, Texas, 78628, United States
Arizona Digestive Health, P.C (ADH)
RECRUITING

Sun City, Arizona, 85351, United States
Asst Degli Spedali Civili Di Brescia
RECRUITING

Brescia, Lombardy, 25123, Italy
Atlanta Gastroenterology Associates
RECRUITING

Atlanta, Georgia, 30342, United States
Azienda Ospedaliera San Gerardo di Monza
RECRUITING

Monza MI, Lombardy, 20900, Italy
Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi-Via Massarenti
RECRUITING

Bologna, Emilia-Romagna, 40138, Italy
Barrie GI Associates
RECRUITING

Barrie, Ontario, L4M 7G1, Canada
Baylor Scott and White Medical Center
RECRUITING

Temple, Texas, 76508, United States
Beijing No.6 Hospital
RECRUITING

Beijing, Beijing Municipality, 100007, China
Boca Clinical Trials Mexico S.C. (Cd. Mexico)
RECRUITING

Miguel Hidalgo, Mexico CITY (federal District), 01120, Mexico
Borzan Polyclinic
RECRUITING

Osijek, 31000, Croatia
Bronglais General Hospital
RECRUITING

Llanrhystud, SY23 1ER, United Kingdom
Burapha University Hospital
RECRUITING

Chon Buri, 20131, Thailand
CECIP - Centro de Estudos Clínicos do Interior Paulista
RECRUITING

Jaú, São Paulo, 17210-190, Brazil
CHU Clermont Ferrand - Hôtel Dieu
RECRUITING

Clermont-Ferrand, 63000, France
CHU St Pierre (St Pierre)
ACTIVE_NOT_RECRUITING

Brussels, 1000, Belgium
CHU Tours - Hôpital Trousseau
RECRUITING

Chambray-lès-Tours, 37170, France
CIUSSS-de-l?Est-de-l?Île-de-Montréal
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
Cano Medical Center
RECRUITING

Harlingen, Texas, 78550, United States
Centro Hospitalar de Entre Douro e Vouga - H. São Sebastião
RECRUITING

Santa Maria da Feira, 4520-211, Portugal
Centro Hospitalar do Algarve - Hospital de Portimao
RECRUITING

Portimão, 8500-338, Portugal
Centro Paulista de Investigacao Clinica - CEPIC
RECRUITING

São Paulo, São Paulo, 04266-010, Brazil
Centro de Investigación Clínica UC-CICUC
RECRUITING

Santiago, 8330034, Chile
Centrum Medyczne CLW-med Aneta Cichomska , Joanna Luka -Wendrowska
WITHDRAWN

Grudzadz, 86-300, Poland
Centrum Medyczne Oporow
RECRUITING

Wroclaw, 52-416, Poland
Centrum Medyczne Promed
RECRUITING

Krakow, 31-513, Poland
Centrum Zdrowia-MDM
RECRUITING

Warsaw, 00-189, Poland
Charlotte Gastroenterology and Hepatology, P.L.L.C
RECRUITING

Charlotte, North Carolina, 28207, United States
China Medical University Hospital
RECRUITING

Taichung, 40447, Taiwan
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44915, United States
Clinical Hospital Center Sestre Milosrdnice
RECRUITING

Zagreb, 10000, Croatia
Clinical Research Center Sp. z o.o. MEDIC-R Spó?ka Komandytowa
RECRUITING

Poznan, 61-731, Poland
Cliniques Universitaires St-Luc
RECRUITING

Brussels, 1200, Belgium
Coral Sea Clinical Research Institute
RECRUITING

Mackay, Queensland, 4740, Australia
Dayton Gastroenterology, Inc.
RECRUITING

Beavercreek, Ohio, 45440, United States
Delta Gastroenterology & Endoscopy Center
RECRUITING

Southaven, Mississippi, 38671, United States
DiGiovanna Inst for Med Ed&Res
RECRUITING

North Massapequa, New York, 11758, United States
Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan
RECRUITING

Dothan, Alabama, 36305, United States
Digestive and Liver Center of Florida
RECRUITING

Orlando, Florida, 32825, United States
Division of Gastroenterology, Depart of Internal Med., Fac of Med., Chiang Mai University
RECRUITING

Chiang Mai, 50200, Thailand
EMC Instytut Medyczny SA
RECRUITING

Późna, 60-309, Poland
ETZ Elisabeth
RECRUITING

Tilburg, 5022 GC, Netherlands
Ellipsis Research Group
RECRUITING

Brooklyn, New York, 11215, United States
Emeritas Research Group
RECRUITING

Lansdowne Town Center, Virginia, 20176, United States
Endoskopia Sp. z o.o.
RECRUITING

Sopot, 81-756, Poland
FAICIC S de R.L. de C.V
RECRUITING

Veracruz, 91900, Mexico
Fakultni nemocnice Ostrava
RECRUITING

Ostrava - Poruba, 708 52, Czechia
Fejer Varmegyei Szent György Egyetemi Oktatokorhaz
RECRUITING

Székesfehérvár, 8000, Hungary
First Affiliated Hospital of Soochow University
RECRUITING

Suzhou, 215006, China
Footscray Hospital
RECRUITING

Footscray, Victoria, 3011, Australia
Frontier Clinical Re search, LLC
RECRUITING

Uniontown, Pennsylvania, 15401, United States
GI Alliance
RECRUITING

Garland, Texas, 75044, United States
GI Alliance - Bay Area Gastroenterology
RECRUITING

Lubbock, Texas, 79410, United States
GI Alliance - Gurnee
RECRUITING

Gurnee, Illinois, 60031, United States
GNRR Digestive Clinics and Research Center Inc.
RECRUITING

Brampton, Ontario, L6S 0E2, Canada
Gabinety Lekarskie Rivermed
RECRUITING

Późna, 61-441, Poland
Gastro Care Associates
RECRUITING

Lancaster, California, 93534, United States
Gastro Health Partners, LLC
RECRUITING

New Albany, Indiana, 47150, United States
Gastro Intestinal Research Institute of Northern Ohio
RECRUITING

Westlake, Ohio, 44145, United States
Gastro One
RECRUITING

Cordova, Tennessee, 38018, United States
Gastroenterology Associates
RECRUITING

Greenville, South Carolina, 29607, United States
Gastroenterology Associates of Central Georgia
RECRUITING

Macon, Georgia, 31201, United States
Gastroenterology Associates of Tidewater
RECRUITING

Chesapeake, Virginia, 23320, United States
Gastroenterology Consultants of SWVA
RECRUITING

Roanoke, Virginia, 24018, United States
Gastroenterology Group Of Rochester, LLP
RECRUITING

Rochester, New York, 14618, United States
Gastroenterology Institute of Orlando
RECRUITING

Orlando, Florida, 32807, United States
Gastromed Kralisz, Romatowski, Stachurska sp.j.
WITHDRAWN

Bia?ystok, 15-322, Poland
General Hospital "Djordje Joanovic"
RECRUITING

Zrenjanin, 23000, Serbia
Grand Teton Research Group, PLLC
RECRUITING

Idaho Falls, Idaho, 83404, United States
Guangzhou First People's Hospital
RECRUITING

Guangzhou, 510180, China
Guardian Angel Research Center, LLC
RECRUITING

Tampa, Florida, 33614, United States
Gujarat Gastro and Vascular Hospital
RECRUITING

Surat, Gujarat, 395009, India
Hepato-Gastroenterologie HK, s.r.o.
RECRUITING

Hradec Králové, 500 12, Czechia
Hi Tech and Global Research, LLC
RECRUITING

Coral Gables, Florida, 33134, United States
Hoag Memorial Hospital Presbyterian;Hoag Center for Research and Education
RECRUITING

Newport Beach, California, 92663, United States
Hospital Britanico
RECRUITING

Ciudad Autonoma Bs As, C1280AEB, Argentina
Hospital Clinico Univ. Lozano Blesa
RECRUITING

Zaragoza, 50009, Spain
Hospital Moinhos de Vento
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-000, Brazil
Hospital Sao Teotonio
RECRUITING

Viseu, 3504-509, Portugal
Hospital Sírio-Libanês
RECRUITING

São Paulo, São Paulo, 01308-050, Brazil
Hospital Universitario Miguel Servet
ACTIVE_NOT_RECRUITING

Zaragoza, 50009, Spain
Hospital Universitario Puerta de Hierro Majadahonda
ACTIVE_NOT_RECRUITING

Majadahonda, Madrid, 28222, Spain
Hospital da Luz Lisboa
RECRUITING

Lisbon, 1500-650, Portugal
Hospital de Braga
RECRUITING

Braga, 4710-243, Portugal
Hospital de Sao Joao
RECRUITING

Porto, 4202-451, Portugal
Huizhou Central People's Hospital
RECRUITING

Huizhou, 516001, China
Hôpital Henri Mondor
RECRUITING

Créteil, 94000, France
Hôpital de Brabois Adultes
RECRUITING

Vandœuvre-lès-Nancy, 54511, France
IRCCS Ospedale Sacro Cuore Don Calabria
RECRUITING

Negrar, Veneto, 37024, Italy
IRCCS Ospedale San Raffaele
RECRUITING

Milan, Lombardy, 20132, Italy
ISCARE a.s.
RECRUITING

Prague, 170 04, Czechia
Illinois Gastroenterology Group-Glenview powered by GI Alliance
RECRUITING

Glenview, Illinois, 60026, United States
Instituto Lobus Unimed Volta Redonda
RECRUITING

Volta Redonda, Rio de Janeiro, 27258-000, Brazil
Instituto Medico CER
RECRUITING

Quilmes, B1878DVB, Argentina
Integrity Advanced Therapeutics PLLC
NOT_YET_RECRUITING

Houston, Texas, 77090, United States
Istituto Clinico Humanitas
RECRUITING

Rozzano (MI), Lombardy, 20089, Italy
James J Peters Veterans Administration Medical Center - NAVREF
RECRUITING

The Bronx, New York, 10468, United States
KM Management spol. s r.o.
RECRUITING

Nitra, 949 01, Slovakia
Kansas Gastroenterology, LLC under Clinical Trials Network
RECRUITING

Wichita, Kansas, 67226-8119, United States
King College Hospital NHS Foundation Trust
RECRUITING

London, SE5 9RS, United Kingdom
Kingsway Hospital
COMPLETED

Nagpur (urban), Maharashtra, 440001, India
Klinical Investigations Group LLC
RECRUITING

San Juan, 00909, Puerto Rico
Klinikum Ernst von Bergmann
RECRUITING

Potsdam, 14467, Germany
Klinikum Wels-Grieskirchen
RECRUITING

Wels, 4600, Austria
LCC Medical Research Institute, LLC
RECRUITING

Miami, Florida, 33126, United States
Leicester General Hospital
RECRUITING

Leicester, LE5 4PW, United Kingdom
London Health Sciences Centre Uni Campus
RECRUITING

London, Ontario, N6A 5A5, Canada
Louisiana Research Center - GastroIntestinal Associates
RECRUITING

Shreveport, Louisiana, 71105, United States
MC " Sveti Ivan Rilski Chudotvorets- 2010
RECRUITING

Plovdiv, 4003, Bulgaria
MIDAS Multispeciality Hospital
RECRUITING

Nagpur (urban), Maharashtra, 440018, India
MZ Badania Slowik Zymla Sp.j.
RECRUITING

Knurów, 44-190, Poland
Macquarie University Hospital
RECRUITING

Macquarie Park, New South Wales, 2109, Australia
Mayo Clinic Hospital
RECRUITING

Scottsdale, Arizona, 85259, United States
Medical Center Kermed
RECRUITING

Bydgoszcz, 85-231, Poland
Medizinisches Zentrum Klinikum Lueneburg
RECRUITING

Lüneburg, 21339, Germany
Medon Clinical Research sp. z o.o
RECRUITING

Warsaw, 02-679, Poland
Medrise sp z o.o
RECRUITING

Lublin, 20-582, Poland
New Cross Hospital
RECRUITING

Wolverhampton, WV10 0QP, United Kingdom
Newdata Clinical Trials
RECRUITING

Aracaju, Sergipe, 49055-000, Brazil
Ohio Gastroenterology Group
RECRUITING

Columbus, Ohio, 43202, United States
Ohio State University
RECRUITING

Hilliard, Ohio, 43026, United States
Om Research LLC
RECRUITING

Apple Valley, California, 92307, United States
Omega Research North Carolina, LLC
RECRUITING

Fuquay-Varina, North Carolina, 27526, United States
One GI: GHP - Gastroenterology Health Partners Louisville
RECRUITING

Louisville, Kentucky, 40218, United States
Ordensklinikum Linz Barmherzige Schwestern
RECRUITING

Linz, 4010, Austria
Ospedale Isola Tiberina Gemelli
RECRUITING

Rome, Lazio, 00186, Italy
Osrodek Badan Klinicznych Bd Research
RECRUITING

I?awa, 14-200, Poland
Peak Gastroenterology Associates
RECRUITING

Colorado Springs, Colorado, 80907, United States
Peterborough City Hospital
RECRUITING

Peterborough, PE 3 9GZ, United Kingdom
Peters Medical Research (PMR), LLC
RECRUITING

High Point, North Carolina, 27260, United States
PlanetMed sp. z o.o.
RECRUITING

Wroc?aw, 52-210, Poland
Policlinico Universitario Campus Biomedico Di Roma
RECRUITING

Rome, Lazio, 00128, Italy
Polyclinique Grand Sud
RECRUITING

Nîmes, 30900, France
Queens Village Medical Care
RECRUITING

Queens Village, New York, 11428, United States
Randomize Now, LLC
RECRUITING

Atlanta, Georgia, 30308, United States
Royal Melbourne Hospital
RECRUITING

Parkville, Victoria, 3050, Australia
Ruijin Hospital Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, 200025, China
SMS Superspeciality Hospital
RECRUITING

Jaipur, Rajasthan, 302007, India
SR Kalla Memorial Gastro & General Hospital
RECRUITING

Jaipur, Rajasthan, 302006, India
Sahyadri Super Speciality Hospital
RECRUITING

Nashik, Maharashtra, 422001, India
Santos Research Center, CORP
RECRUITING

Tampa, Florida, 33615, United States
Second Multiprofile Hospital For Active Treatment-Sofia
WITHDRAWN

Sofia Town, Sofia, 1202, Bulgaria
Semmelweis Egyetem
RECRUITING

Budapest, 1082, Hungary
Shengjing Hospital of China Medical University
RECRUITING

Shenyang, 110004, China
Sir Run Run Shaw Hospital Zhejiang University
RECRUITING

Hangzhou, 310016, China
Sonomed Sp. z o.o.
RECRUITING

Szczecin, 71-685, Poland
Soroka Medical Center
RECRUITING

Beersheba, 8410101, Israel
Southern Star Research Institute, LLC.
RECRUITING

San Antonio, Texas, 78229, United States
Stanford Medicine Outpatient Center
RECRUITING

Redwood City, California, 94063, United States
Stepping Hill Hospital
RECRUITING

Stockport, SK2 7JE, United Kingdom
Sunpasitthiprasong Hospital
RECRUITING

Ubonratchathani, 34000, Thailand
Surat Institute of Digestive Sciences Hospitals
RECRUITING

Surat, Gujarat, 395002, India
Szpital Miejski sw. Jana Paw?a II w Elblagu
RECRUITING

Elblag, 82-300, Poland
Szpital Zakonu Bonifratrow Sw. Jana Bozego w Lodzi sp. z o.o.
RECRUITING

?ód?, 93-357, Poland
TDDC GI Alliance research Webster
RECRUITING

Webster, Texas, 77598, United States
TDDC dba GI Alliance Research
NOT_YET_RECRUITING

Mansfield, Texas, 76063, United States
TIDHI Innovation Inc.
RECRUITING

Toronto, Ontario, M6A 3B4, Canada
Texas Digestive Specialists
RECRUITING

Harlingen, Texas, 78550, United States
The Affiliated Hospital of Medical College Qingdao University
RECRUITING

Qingdao, 266000, China
The Chaim Sheba Medical Center
RECRUITING

Ramat Gan, 5265601, Israel
The First Affiliate Hospital of Guangxi Medical University
RECRUITING

Nanning, 530021, China
The First Affiliated Hospital of Ningbo University
RECRUITING

Ningbo, 315000, China
The First Affiliated Hospital of Xiamen University
RECRUITING

Xiamen, 361003, China
The First Affilliated Hospital of Kunming Medical University
RECRUITING

Kunming, Yunnan, 650032, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330008, China
The Sister Life Research
RECRUITING

Hialeah, Florida, 33013, United States
The second Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, 510260, China
Third Xiangya Hospital Centrel South University
RECRUITING

Changsha, 410013, China
Tyler Research Institute, LLC
RECRUITING

Tyler, Texas, 75701, United States
Uni of Texas Medical Branch
RECRUITING

Galveston, Texas, 77555, United States
University Gastroenterology
RECRUITING

Providence, Rhode Island, 02904, United States
University of Cincinnati Hospital
RECRUITING

Cincinnati, Ohio, 45267, United States
University of South Florida School of Medicine Morsani Center for Advanced Health Care
RECRUITING

Tampa, Florida, 33612, United States
University of Texas Health Center at Tyler
RECRUITING

Tyler, Texas, 75708, United States
Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Valley View Internal Medicine
RECRUITING

Garden Grove, California, 92845, United States
Vas-Oxy Egeszsegugyi Kft
RECRUITING

Szombathely, 9700, Hungary
Vasutegeszsegugyi Kft. - Debreceni Egeszsegugyi Kozpont
RECRUITING

Debrecen, 4025, Hungary
Vivamed Spolka Z Ograniczona Odpowiedzialnoscia
RECRUITING

Warsaw, 03-580, Poland
Weill Cornell Medical College
RECRUITING

New York, New York, 10021, United States
West China Hospital of Sichuan University
RECRUITING

Chengdu, 610041, China
Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
RECRUITING

Shanghai, 200092, China
Yashoda Hospitals
RECRUITING

Secunderabad, Telangana, 500003, India
Zhongshan Hospital Xiamen University
RECRUITING

Xiamen, 361004, China
Ålborg Universitets Hospital
RECRUITING

Aalborg, 9000, Denmark
Észak-Pesti Centrumkórház-Honvédkórház
RECRUITING

Budapest, 1062, Hungary

Conditions

Explore the condition pages connected to this study.

MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS