New cancer gel shows promise for rare urinary tract tumors

NCT ID NCT06774131

Recruiting now Disease control Sponsor: UroGen Pharma Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new gel-like drug, UGN-104, placed directly into the upper urinary tract to treat low-grade cancer. About 70 adults with small tumors will receive the treatment to see if it can completely eliminate visible cancer. The goal is to control the disease and avoid more invasive surgery.

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Conditions

The condition(s) this trial relates to.

renal pelvis/ureter urothelial carcinoma transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UPPER URINARY TRACT UROTHELIAL CARCINOMA UROTHELIAL CARCINOMA

Contacts and locations

Locations

"Dr. Carol Davila" Nephrology Clinical Hospital Bucharest
RECRUITING

Bucharest, Romania
Amarillo Urology Research
COMPLETED

Amarillo, Texas, 79106, United States
Arizona State Urological Research Institute, LLC ("ASURI")
RECRUITING

Chandler, Arizona, 85225, United States
Assaf Harofeh hospital, Shamir Medical Center
RECRUITING

Ẕerifin, 70500, Israel
Bihor County Emergency Clinical Hospital
RECRUITING

Oradea, 410169, Romania
Bioresearch Partner - Aventura
RECRUITING

Aventura, Florida, 33180, United States
Bioresearch Partner - Hialeah Hospital
RECRUITING

Hialeah, Florida, 33013, United States
Carolina Urologic Research Center, LLC
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
Clinical Hospital of the Ministry of Internal Affairs and Administration with Warmia and Mazury Oncology Centre in Olsztyn
RECRUITING

Olsztyn, 10-228, Poland
D&H National Research Centers - Cancer Research Center, LLC
RECRUITING

Margate, Florida, 33063, United States
Delta Health Care S.R.L.
RECRUITING

Bucharest, Romania
East Valley Urology Center of Arizona
RECRUITING

Queen Creek, Arizona, 85140, United States
Guram Karazanashvili Robotic Center LLC
RECRUITING

Tbilisi, Georgia
Hospital Clínico Universitario de Valencia
RECRUITING

Valencia, 46010, Spain
Hospital General Universitario Morales Meseguer
RECRUITING

Murcia, 30008, Spain
Hospital Universitario Puerta del Mar
RECRUITING

Cadiz, 11009, Spain
Hospital Universitario Reina Sofía
RECRUITING

Córdoba, 14004, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
IN-VIVO Limited Liability Company
RECRUITING

Bydgoszcz, 85-048, Poland
Independent Public Teaching Hospital #2
RECRUITING

Szczecin, 70-111, Poland
JSC "Vian"-I.Bokeria University Hospital
RECRUITING

Tbilisi, 0137, Georgia
JSC Jerarsi
RECRUITING

Tbilisi, Georgia
Jan Mikulicz-Radecki University Clinical Hospital in Wroclaw
RECRUITING

Wroclaw, 50-556, Poland
LTD "Geo Hospitals"
RECRUITING

Tbilisi, 0144, Georgia
LTD "Israel-Georgian Medical Research Clinic "Healthycore"
RECRUITING

Tbilisi, 0112, Georgia
LTD "Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic"
RECRUITING

Tbilisi, 0144, Georgia
LTD West Regional Center of Modern Medical Technologies
RECRUITING

Kutaisi, Imereti, Georgia
Lady Davis Carmel Medical Center
RECRUITING

Haifa, 3436212, Israel
Low county Urology Clinics
RECRUITING

North Charleston, South Carolina, 29406, United States
MHAT Haskovo AD
RECRUITING

Haskovo, 6300, Bulgaria
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Meir Medical Center, Department of Urology
RECRUITING

Kefar Sava, 4428164, Israel
Michael G Oefelein Clinical Trials
RECRUITING

Bakersfield, California, 93301, United States
Montefiore Medical Center - Bronx
RECRUITING

The Bronx, New York, 10461, United States
Municipal Clinical Hospital Cluj-Napoca
RECRUITING

Cluj-Napoca, 400139, Romania
NZOZ Silesian Urology Hospital
RECRUITING

Katowice, 40-073, Poland
P. Stradins Clinical University Hospital, Center for Urology
RECRUITING

Riga, Latvia
Penn State Milton S Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Rabin Medical Center - Hasharon hospital
RECRUITING

Petah Tikva, 4937211, Israel
Regional Institute of Oncology Iasi
RECRUITING

Iași, 700483, Romania
Renovatio Clinical - The Woodlands Research Center
RECRUITING

The Woodlands, Texas, 77380, United States
Semmelweis University, Department of Urology
COMPLETED

Budapest, Hungary
Sheba Medical Center
RECRUITING

Ramat Gan, 5262000, Israel
St. John of Dukla Oncology Center of Lublin Land
RECRUITING

Lublin, 20-090, Poland
Texas Urology Specialists-Austin
RECRUITING

Austin, Texas, 78705, United States
The James Cancer Hospital and Solove Research Institute
RECRUITING

Columbus, Ohio, 43210, United States
The Urology Center, P.C.
COMPLETED

Omaha, Nebraska, 68114, United States
Timisoara County Clinical Emergency Hospital Pius Brinzeu
RECRUITING

Timișoara, 300723, Romania
UC Irvine Health. Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States
UPNT Research Institute, LLC
RECRUITING

Arlington, Texas, 76017, United States
University Clinical Center in Gdansk, Department of urology
RECRUITING

Gdansk, Pomeranian, Poland
University Hospital Complex A Coruna (CHUAC), Department of Urology
RECRUITING

A Coruña, Galicia, Spain
University Hospital Ramon y Cajal
RECRUITING

Madrid, Madrid, Spain
University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I. Pirogov," Sofia, Clinic of Urology
RECRUITING

Sofia, 1000, Bulgaria
University of Arkansas for Medical Sciences
RECRUITING

Arkansas City, Arkansas, 72205, United States
University of Cincinnati Medical Center (UCMC)
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Debrecen Clinical Center, Department of Urology
RECRUITING

Debrecen, 4032, Hungary
University of Florida Health (UF Health), Cancer Center
RECRUITING

Gainesville, Florida, 32610, United States
University of Virginia Comprehensive Cancer Center
RECRUITING

Charlottesville, Virginia, 22908, United States
Urologic Specialists of Oklahoma
RECRUITING

Tulsa, Oklahoma, 74146-5830, United States
Urology Center of Iowa Research
RECRUITING

Clive, Iowa, 50325, United States
Urology Centers of Alabama
RECRUITING

Homewood, Alabama, 35209, United States

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