New cancer gel shows promise for rare urinary tract tumors

NCT ID NCT06774131

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new gel-like drug, UGN-104, placed directly into the upper urinary tract to treat low-grade cancer. About 70 adults with small tumors will receive the treatment to see if it can completely eliminate visible cancer. The goal is to control the disease and avoid more invasive surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal pelvis/ureter urothelial carcinoma transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • "Dr. Carol Davila" Nephrology Clinical Hospital Bucharest

    RECRUITING

    Bucharest, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Amarillo Urology Research

    COMPLETED

    Amarillo, Texas, 79106, United States

  • Arizona State Urological Research Institute, LLC ("ASURI")

    RECRUITING

    Chandler, Arizona, 85225, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Assaf Harofeh hospital, Shamir Medical Center

    RECRUITING

    Ẕerifin, 70500, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Bihor County Emergency Clinical Hospital

    RECRUITING

    Oradea, 410169, Romania

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bioresearch Partner - Aventura

    RECRUITING

    Aventura, Florida, 33180, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bioresearch Partner - Hialeah Hospital

    RECRUITING

    Hialeah, Florida, 33013, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Carolina Urologic Research Center, LLC

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Clinical Hospital of the Ministry of Internal Affairs and Administration with Warmia and Mazury Oncology Centre in Olsztyn

    RECRUITING

    Olsztyn, 10-228, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • D&H National Research Centers - Cancer Research Center, LLC

    RECRUITING

    Margate, Florida, 33063, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Delta Health Care S.R.L.

    RECRUITING

    Bucharest, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • East Valley Urology Center of Arizona

    RECRUITING

    Queen Creek, Arizona, 85140, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guram Karazanashvili Robotic Center LLC

    RECRUITING

    Tbilisi, Georgia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clínico Universitario de Valencia

    RECRUITING

    Valencia, 46010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital General Universitario Morales Meseguer

    RECRUITING

    Murcia, 30008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Puerta del Mar

    RECRUITING

    Cadiz, 11009, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Reina Sofía

    RECRUITING

    Córdoba, 14004, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Virgen Macarena

    RECRUITING

    Seville, 41009, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IN-VIVO Limited Liability Company

    RECRUITING

    Bydgoszcz, 85-048, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Independent Public Teaching Hospital #2

    RECRUITING

    Szczecin, 70-111, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • JSC "Vian"-I.Bokeria University Hospital

    RECRUITING

    Tbilisi, 0137, Georgia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • JSC Jerarsi

    RECRUITING

    Tbilisi, Georgia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jan Mikulicz-Radecki University Clinical Hospital in Wroclaw

    RECRUITING

    Wroclaw, 50-556, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • LTD "Geo Hospitals"

    RECRUITING

    Tbilisi, 0144, Georgia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • LTD "Israel-Georgian Medical Research Clinic "Healthycore"

    RECRUITING

    Tbilisi, 0112, Georgia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • LTD "Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic"

    RECRUITING

    Tbilisi, 0144, Georgia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • LTD West Regional Center of Modern Medical Technologies

    RECRUITING

    Kutaisi, Imereti, Georgia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lady Davis Carmel Medical Center

    RECRUITING

    Haifa, 3436212, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Low county Urology Clinics

    RECRUITING

    North Charleston, South Carolina, 29406, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MHAT Haskovo AD

    RECRUITING

    Haskovo, 6300, Bulgaria

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Meir Medical Center, Department of Urology

    RECRUITING

    Kefar Sava, 4428164, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Michael G Oefelein Clinical Trials

    RECRUITING

    Bakersfield, California, 93301, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Montefiore Medical Center - Bronx

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Municipal Clinical Hospital Cluj-Napoca

    RECRUITING

    Cluj-Napoca, 400139, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NZOZ Silesian Urology Hospital

    RECRUITING

    Katowice, 40-073, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • P. Stradins Clinical University Hospital, Center for Urology

    RECRUITING

    Riga, Latvia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Penn State Milton S Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rabin Medical Center - Hasharon hospital

    RECRUITING

    Petah Tikva, 4937211, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Regional Institute of Oncology Iasi

    RECRUITING

    Iași, 700483, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Renovatio Clinical - The Woodlands Research Center

    RECRUITING

    The Woodlands, Texas, 77380, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Semmelweis University, Department of Urology

    COMPLETED

    Budapest, Hungary

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, 5262000, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. John of Dukla Oncology Center of Lublin Land

    RECRUITING

    Lublin, 20-090, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Texas Urology Specialists-Austin

    RECRUITING

    Austin, Texas, 78705, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The James Cancer Hospital and Solove Research Institute

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Urology Center, P.C.

    COMPLETED

    Omaha, Nebraska, 68114, United States

  • Timisoara County Clinical Emergency Hospital Pius Brinzeu

    RECRUITING

    Timișoara, 300723, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC Irvine Health. Chao Family Comprehensive Cancer Center

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UPNT Research Institute, LLC

    RECRUITING

    Arlington, Texas, 76017, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Clinical Center in Gdansk, Department of urology

    RECRUITING

    Gdansk, Pomeranian, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital Complex A Coruna (CHUAC), Department of Urology

    RECRUITING

    A Coruña, Galicia, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Ramon y Cajal

    RECRUITING

    Madrid, Madrid, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Multiprofile Hospital for Active Treatment and Emergency Medicine "N.I. Pirogov," Sofia, Clinic of Urology

    RECRUITING

    Sofia, 1000, Bulgaria

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arkansas for Medical Sciences

    RECRUITING

    Arkansas City, Arkansas, 72205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati Medical Center (UCMC)

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Debrecen Clinical Center, Department of Urology

    RECRUITING

    Debrecen, 4032, Hungary

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Florida Health (UF Health), Cancer Center

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Virginia Comprehensive Cancer Center

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Urologic Specialists of Oklahoma

    RECRUITING

    Tulsa, Oklahoma, 74146-5830, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Urology Center of Iowa Research

    RECRUITING

    Clive, Iowa, 50325, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Urology Centers of Alabama

    RECRUITING

    Homewood, Alabama, 35209, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••