Experimental cell therapy takes aim at Hard-to-Treat kidney cancer

NCT ID NCT07500805

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new cell therapy called UCL70805F in 21 people with advanced clear cell kidney cancer that has not responded to standard treatments. The therapy uses immune cells designed to target a protein called CD70 on cancer cells. The main goals are to check safety and see if the treatment can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
UCL70805F (a type of cell therapy using immune cells to target CD70 on cancer cells)
What this could lead to
If it works, this could point toward a new treatment option for advanced kidney cancer that has stopped responding to standard therapies.
What could go wrong
This is a very early Phase 1 trial with only 21 participants, so it is primarily testing safety. The treatment may not shrink tumors or could cause serious side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China