New pill takes on tough blood cancers in first human trial

NCT ID NCT06590961

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests an experimental oral drug called UBX-303061 in 94 adults with B-cell blood cancers (like certain lymphomas and leukemias) that have come back or not responded to at least two prior treatments. The main goals are to check safety, find the right dose, and see if the drug shows any anti-cancer activity. It is a first-in-human study, so results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UBX-303061 (oral drug)

What this could lead to

If successful, this could point toward a new oral treatment option for certain blood cancers that have stopped responding to other therapies.

What could go wrong

This is a very early, first-in-human trial with only 94 participants. The drug may not prove safe or effective, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RELAPSED/REFRACTORY B-CELL MALIGNANCIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neoplasm of mature B-cells Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AidPort

    NOT_YET_RECRUITING

    Grodzisk Wielkopolski, Wielkopolskie Voivodeship, 62-065, Poland

  • Asan Medical Center

    RECRUITING

    Seoul, Seoul, 05505, South Korea

  • Gabrail Cancer Center

    RECRUITING

    Canton, Oklahoma, 44718, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • MICS Centrum Medyczne Toruń

    NOT_YET_RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • Pratia, MTZ Clinical Research

    NOT_YET_RECRUITING

    Warsaw, Mazowieckie Voivodeship, 02-172, Poland

  • Pratia, Oncology Katowice

    NOT_YET_RECRUITING

    Katowice, Silesian Voivodeship, 40-519, Poland

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul, 06351, South Korea

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    RECRUITING

    Seoul, Seoul, 06591, South Korea

  • The Catholic University of Korea, Yeouido St. Mary's Hospital

    RECRUITING

    Seoul, Seoul, 07345, South Korea

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States