New pill takes on tough blood cancers in first human trial

NCT ID NCT06590961

Recruiting now Disease control Sponsor: Ubix Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests an experimental oral drug called UBX-303061 in 94 adults with B-cell blood cancers (like certain lymphomas and leukemias) that have come back or not responded to at least two prior treatments. The main goals are to check safety, find the right dose, and see if the drug shows any anti-cancer activity. It is a first-in-human study, so results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: UBX-303061 (oral drug)
What this could lead to: If successful, this could point toward a new oral treatment option for certain blood cancers that have stopped responding to other therapies.
What could go wrong: This is a very early, first-in-human trial with only 94 participants. The drug may not prove safe or effective, and side effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm of mature B-cells Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSED/REFRACTORY B-CELL MALIGNANCIES

Contacts and locations

Locations

AidPort
NOT_YET_RECRUITING

Grodzisk Wielkopolski, Wielkopolskie Voivodeship, 62-065, Poland
Asan Medical Center
RECRUITING

Seoul, Seoul, 05505, South Korea
Gabrail Cancer Center
RECRUITING

Canton, Oklahoma, 44718, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
MICS Centrum Medyczne Toruń
NOT_YET_RECRUITING

Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
Pratia, MTZ Clinical Research
NOT_YET_RECRUITING

Warsaw, Mazowieckie Voivodeship, 02-172, Poland
Pratia, Oncology Katowice
NOT_YET_RECRUITING

Katowice, Silesian Voivodeship, 40-519, Poland
Samsung Medical Center
RECRUITING

Seoul, Seoul, 06351, South Korea
The Catholic University of Korea, Seoul St. Mary's Hospital
RECRUITING

Seoul, Seoul, 06591, South Korea
The Catholic University of Korea, Yeouido St. Mary's Hospital
RECRUITING

Seoul, Seoul, 07345, South Korea
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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