New hope for Tough-to-Treat lymphoma: experimental combo trial opens

NCT ID NCT06743503

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This early-stage study tests an experimental drug (UB-VV400) alone and with rapamycin in adults with aggressive B-cell lymphoma that has returned or not responded to treatment. About 70 participants will receive the therapy to find the safest dose and check for side effects. The goal is to offer a new option for patients who have limited choices, including those who have already tried CAR T-cell therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences

    NOT_YET_RECRUITING

    Tianjin, China

    Contact

    Contact

  • The First Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, China

    Contact

Conditions

Explore the condition pages connected to this study.