Can a common amino acid outperform chemotherapy cream to restore skin color?
NCT ID NCT07742982
First seen Aug 03, 2026 · Last updated Aug 12, 2026 · Updated 3 times
Summary
This trial tests whether applying tyrosine or 5-fluorouracil to the skin, combined with a fractional erbium YAG laser, can help restore color in people with focal vitiligo. Vitiligo is an autoimmune condition that causes white patches by destroying pigment-making cells. The study will measure changes in the Vitiligo Area Scoring Index to see which treatment works better. Around 40 adults with focal vitiligo will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Topical tyrosine or topical 5-fluorouracil, each combined with fractional erbium YAG laser
- What this could lead to
- If successful, this could point toward a more effective treatment to restore skin color in people with focal vitiligo.
- What could go wrong
- This is a small early-phase trial, so results may not apply broadly. Treatments may cause skin irritation or fail to produce lasting repigmentation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FOCAL VITILIGO are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aswan University Hospital
RECRUITINGAswān, Egypt