New pill targets bladder Cancer's genetic weakness

NCT ID NCT06995677

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 24 times

Summary

This study tests a new drug called TYRA-300 in people with a low-grade, intermediate-risk bladder cancer that has not invaded the muscle. The drug targets tumors with specific changes in the FGFR3 gene. About 90 adults will take the drug to see if it shrinks tumors and delays cancer return, while monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASL Napoli 2 Nord - Ospedale Santa Maria delle Grazie

    RECRUITING

    Pozzuoli, 80078, Italy

  • Arkansas Urology

    RECRUITING

    Little Rock, Arkansas, 72211, United States

  • Associate Urologist of North Carolina

    RECRUITING

    Raleigh, North Carolina, 27612, United States

  • Associated Medical Professionals of NY

    RECRUITING

    Syracuse, New York, 13210, United States

  • Associated Urological Specialists

    RECRUITING

    Chicago Ridge, Illinois, 60415, United States

  • Atlantic Health System

    RECRUITING

    Morristown, New Jersey, 07960, United States

  • Azienda Ospedaliero Universitaria Pisana - Ospedale Santa Chiara

    RECRUITING

    Pisa, 56126, Italy

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

  • Carolina Urologic Research Center

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

  • Centro Médico Teknon

    RECRUITING

    Barcelona, Spain, 08003, Spain

  • Conrad Pearson-Memphis

    RECRUITING

    Germantown, Tennessee, 38138, United States

  • Duke Cancer Institute

    RECRUITING

    Durham, North Carolina, 27705, United States

  • Duly Health and Care

    RECRUITING

    Lisle, Illinois, 60532, United States

  • Epworth Freemasons-Victoria Parade

    RECRUITING

    Richmond, Victoria, 3121, Australia

  • First Urology

    RECRUITING

    Jeffersonville, Indiana, 47130, United States

  • Hospital Clínico San Carlos

    ACTIVE_NOT_RECRUITING

    Madrid, Spain, 28040, Spain

  • Hospital Quirón Barcelona

    RECRUITING

    Barcelona, 08908, Spain

  • Hospital Universitario 12 de Oc

    RECRUITING

    Madrid, Spain, 28041, Spain

  • Hospital Universitario Marqués de Valdecilla

    RECRUITING

    Santander, 39008, Spain

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Istituti Fisioterapici Ospitalieri (IFO)

    RECRUITING

    Rome, Italy, Italy

  • Istituto Europeo di Oncologia

    RECRUITING

    Milan, 20141, Italy

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21205, United States

  • Keystone Urology Specialists

    RECRUITING

    Lancaster, Pennsylvania, 17604, United States

  • Lowcounty Urology Clinics, P.A.

    RECRUITING

    North Charleston, South Carolina, 29406, United States

  • MD Anderson Cancer Center - Madrid

    RECRUITING

    Madrid, 28003, Spain

  • Memorial Sloan Kettering Cancer Center - Sidney Kimmel Center for Prostate and Urologic Cancers

    RECRUITING

    New York, New York, 10065, United States

  • MidLantic Urology

    RECRUITING

    Bala-Cynwyd, Pennsylvania, 19004, United States

  • New Jersey Urology, LLC (Summit Health - Washington Township)

    RECRUITING

    Voorhees Township, New Jersey, 08043, United States

  • Om Research LLC

    RECRUITING

    San Diego, California, 92123, United States

  • Oregon Urology Institute

    RECRUITING

    Springfield, Ohio, 97477, United States

  • The Bronx Veterans Medical Research Foundation, Inc.

    RECRUITING

    The Bronx, New York, 10468, United States

  • Tri Valley Urology - Murrieta

    RECRUITING

    Murrieta, California, 92562, United States

  • University of Kansas Medical Center (KUMC)

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • Urology Associates PC

    RECRUITING

    Nashville, Tennessee, 37209, United States

  • Urology Austin

    RECRUITING

    Austin, Texas, 78759, United States

  • Urology Centers of Alabama

    RECRUITING

    Homewood, Alabama, 35209, United States

  • Urology San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.