Typhoid vaccine study probes hidden immune changes in the gut

NCT ID NCT03970304

First seen Jan 08, 2026 · Last updated Apr 30, 2026 · Updated 16 times

Summary

This study looks at how the typhoid vaccine changes the immune system and bacteria in the gut. About 87 adults who are already having a colonoscopy will either get the vaccine before or after the procedure, or not get it at all. Researchers will collect tissue, blood, saliva, and stool samples to measure immune cell responses. The goal is to learn more about how the vaccine works, not to treat or prevent disease in the participants.

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Contacts and locations

Locations

  • Universtiy of Maryland, Baltimore, Center for Vaccine Development and Global Health

    Baltimore, Maryland, 21201, United States

Conditions

Explore the condition pages connected to this study.