Booster shot for typhoid: could it protect kids for years?

NCT ID NCT07624175

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a booster dose of typhoid vaccine given 5-6 years after the first shot still works in children. Researchers measured immune responses and side effects in 147 children in Burkina Faso. The goal is to understand how long protection lasts and if boosters are needed in areas where typhoid is a serious threat.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

typhoid conjugate vaccine (Vi-CRM)

What this could lead to

If successful, this could show that a booster dose of typhoid vaccine provides lasting protection for children in areas where typhoid is common.

What could go wrong

This is a small, completed Phase 2 study with 147 children, so results may not apply to larger populations. The vaccine may not provide long-term immunity or may cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

typhoid fever prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Schiphra Protestant Hospital

    Ouagadougou, Burkina Faso