Booster shot for typhoid: could it protect kids for years?
NCT ID NCT07624175
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether a booster dose of typhoid vaccine given 5-6 years after the first shot still works in children. Researchers measured immune responses and side effects in 147 children in Burkina Faso. The goal is to understand how long protection lasts and if boosters are needed in areas where typhoid is a serious threat.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- typhoid conjugate vaccine (Vi-CRM)
- What this could lead to
- If successful, this could show that a booster dose of typhoid vaccine provides lasting protection for children in areas where typhoid is common.
- What could go wrong
- This is a small, completed Phase 2 study with 147 children, so results may not apply to larger populations. The vaccine may not provide long-term immunity or may cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Schiphra Protestant Hospital
Ouagadougou, Burkina Faso
More trials for these conditions
Other studies related to the condition(s) this trial covers.