Can a simple drug cut blood loss in extreme pelvic surgery?

NCT ID NCT03128866

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 26 times

Summary

This early-stage trial tests whether tranexamic acid (TXA) can reduce blood loss in patients with pelvic tumors undergoing hemipelvectomy, a surgery that removes part of the pelvis. About 80 adults and children will receive TXA or a placebo during surgery. The goal is to see if TXA helps stabilize blood clots and lower the need for blood transfusions.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.