Could fewer pills fight this tough lung bug just as well?

NCT ID NCT03672630

Summary

This study aimed to find out if a simpler, two-antibiotic treatment is as effective as the standard three-antibiotic regimen for a chronic lung infection called MAC. Researchers enrolled 474 adults with the infection to see if using fewer drugs could reduce common and sometimes severe side effects—like nausea, hearing loss, and fatigue—without losing the ability to clear the infection. The goal was to make long-term treatment more tolerable for patients.

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Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Kaiser Permanente Hawaii

    Honolulu, Hawaii, 96817, United States

  • Loma Linda University Medical Center

    Loma Linda, California, 92354, United States

  • Louisina State University

    New Orleans, Louisiana, 70112, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • New York University

    New York, New York, 10016, United States

  • Northwell Health

    Manhasset, New York, 11030, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Tampa VA Medical Center

    Tampa, Florida, 33612, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • University Health Network

    Toronto, Ontario, M5T2S8, Canada

  • University of California, San Diego

    San Diego, California, 92103, United States

  • University of California, San Francisco

    San Francisco, California, 94110, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Kansas

    Kansas City, Kansas, 66160, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

  • University of Texas Health Science Center

    Tyler, Texas, 75708, United States

  • University of Washington

    Seattle, Washington, 98104, United States

  • University of Wisconsin School of Medicine and Public Health

    Madison, Wisconsin, 53705, United States

  • Vancouver Clinic

    Vancouver, Washington, 98664, United States

Conditions

Explore the condition pages connected to this study.