Twin pregnancy breakthrough? stitch plus hormone may stop preterm birth

NCT ID NCT07319715

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a surgical stitch (cervical cerclage) plus a hormone gel (vaginal progesterone) works better than standard care to prevent preterm birth in women carrying twins with a short cervix. 59 women participated, and researchers also checked if the treatment reduced inflammation in cervical fluid. The goal is to help twins reach full term and improve health outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vaginal progesterone

What this could lead to

If successful, this combined approach could offer a new way to reduce preterm births in twin pregnancies, improving outcomes for mothers and babies.

What could go wrong

This is a small Phase 2 trial with only 59 participants, so results may not apply to all twin pregnancies. The procedure and medication carry risks like infection or side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Benha University

    Banhā, Qalyubia Governorate, 13511, Egypt