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Lung cancer drug combo trial halted early

NCT ID NCT04524689

Terminated Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug (tusamitamab ravtansine) combined with pembrolizumab and chemotherapy in 57 people with advanced non-squamous non-small-cell lung cancer that has a specific marker (CEACAM5). The goal was to see if the combination was safe and shrank tumors. The trial was terminated early, so results are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SQUAMOUS NON-SMALL-CELL LUNG CANCER (NSQ NSCLC)

Contacts and locations

Locations

  • CHRU BREST 5 Avenue Foch_Investigational Site Number :2500003

    Brest, 29200, France

  • Centre François Magendie Hôpital du Haut Lévèque Av.de Magellan_Investigational Site Number :2500001

    Pessac, 33600, France

  • Centro Avancado de Oncologia CECAN - Liga Contra o Cancer Site Number : 0760004

    Natal, Rio Grande do Norte, 59062-000, Brazil

  • Centro de Investigacion y Desarrollo Oncologico (CIDO) Hochstetter 599 of. 602-603-1001, Temuco_Investigational Site Number :1520005

    Temuco, La Araucanía, 4780000, Chile

  • Fakultní nemocnice Olomouc Onkologická klinika I.P. Pavlova 6_Site Number :2030001

    Olomouc, 77900, Czechia

  • ICEGCLINIC Avenida Serafín Zamora 190 Torre B, piso 4. La Florida_Investigational Site Number :1520006

    Santiago, 8241470, Chile

  • Institut Sainte-Catherine 250 Chemin de Baigne-Pieds_Investigational Site Number :2500005

    Avignon, 84918, France

  • Investigational Site Number : 3760001

    Ramat Gan, 5266202, Israel

  • Investigational Site Number : 3760002

    Tel Aviv, 64239, Israel

  • Investigational Site Number : 7240001

    Madrid, 28041, Spain

  • Investigational Site Number : 7240002

    Las Palmas, 35016, Spain

  • Investigational Site Number : 7240004

    Madrid, 28040, Spain

  • Investigational Site Number : 7240005

    A Coruña, A Coruña [La Coruña], 15006, Spain

  • Investigational Site Number : 7240006

    Badalona, Catalunya [Cataluña], 08916, Spain

  • Investigational Site Number : 7240007

    Oviedo, Principality of Asturias, 33011, Spain

  • KU Medical Center_Investigational Site Number :8400002

    Westwood, Kansas, 66205, United States

  • Nemocnice AGEL Ostrava - Vitkovice Plicní oddělení Zalužanského 2214/35_Site Number :2030002

    Ostrava - Vitkovice, 70384, Czechia

  • ONCOCENTRO APYS Av. La Marina 1702, 2do piso, Viña del Mar_Investigational Site Number :1520003

    Viña del Mar, Valparaiso, 2520598, Chile

  • Orlandi Oncologia General Salvo 159, Providencia_Investigational Site Number :1520002

    Santiago, 7500713, Chile

  • Országos Onkológiai Intézet Ráth György u. 7_Investigational Site Number :3480002

    Budapest, 1122, Hungary

  • Pôle régional de Cancérologie 2 rue de la Milèterie BP 577_Investigational Site Number :2500004

    Poitiers, 86021, France

  • Veszprém Megyei Tüdőgyógyintézet 049/2 Hrsz_Investigational Site Number :3480004

    Farkasgyepü, 8582, Hungary