New combo therapy aims to shrink prostate cancer tumors
NCT ID NCT07190300
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called tulmimetostat combined with standard hormone therapies (darolutamide or abiraterone) in men whose prostate cancer has spread but still responds to hormone treatment. The goal is to see if the combination is safe and works better than standard care alone. About 181 men will take part, first in a small dose-finding phase, then in a larger phase comparing the combo to darolutamide alone.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC HORMONE-SENSITIVE PROSTATE CANCER (MHSPC) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Carolina Urologic Research Center
RECRUITINGMyrtle Beach, South Carolina, 29572, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
Contact
Contact Email: •••••@•••••
-
Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Email: •••••@•••••
Contact
-
Medical University of South Carolina MUSC
RECRUITINGCharleston, South Carolina, 29425, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Novartis Investigative Site
WITHDRAWNCamperdown, New South Wales, 2050, Australia
-
Novartis Investigative Site
RECRUITINGWollongong, New South Wales, 2500, Australia
-
Novartis Investigative Site
RECRUITINGPorto Alegre, Rio Grande do Sul, 90610-001, Brazil
-
Novartis Investigative Site
RECRUITINGMontreal, Quebec, H2X 1R9, Canada
-
Novartis Investigative Site
RECRUITINGGuangzhou, 510060, China
-
Novartis Investigative Site
RECRUITINGCréteil, 94010, France
-
Novartis Investigative Site
RECRUITINGLille, 59020, France
-
Novartis Investigative Site
RECRUITINGNantes, 44093, France
-
Novartis Investigative Site
RECRUITINGJena, Thuringia, 07740, Germany
-
Novartis Investigative Site
RECRUITINGEssen, 45147, Germany
-
Novartis Investigative Site
RECRUITINGHong Kong, 999077, Hong Kong
-
Novartis Investigative Site
RECRUITINGBudapest, H 1122, Hungary
-
Novartis Investigative Site
RECRUITINGBudapest, H-1083, Hungary
-
Novartis Investigative Site
RECRUITINGSzeged, 6725, Hungary
-
Novartis Investigative Site
RECRUITINGRozzano, MI, 20089, Italy
-
Novartis Investigative Site
RECRUITINGVerona, VR, 37134, Italy
-
Novartis Investigative Site
RECRUITINGSeoul, 05505, South Korea
-
Novartis Investigative Site
RECRUITINGSeoul, 06591, South Korea
-
Novartis Investigative Site
RECRUITINGMadrid, 28034, Spain
-
Novartis Investigative Site
RECRUITINGMadrid, 28040, Spain
-
Novartis Investigative Site
RECRUITINGMadrid, 28222, Spain
-
Novartis Investigative Site
RECRUITINGAnkara, Sihhiye-Altindag, 06230, Turkey (Türkiye)
-
Novartis Investigative Site
RECRUITINGLondon, W1G 6AD, United Kingdom
-
Uni Of Iowa Hospitals And Clinics
RECRUITINGIowa City, Iowa, 52242, United States
Contact
Contact Email: •••••@•••••
-
Univ of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294-3300, United States
Contact
Contact Email: •••••@•••••
-
University of Kansas Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
Contact
Contact Email: •••••@•••••
-
Wichita Urology Group PA
RECRUITINGWichita, Kansas, 67226, United States
Contact
Contact Email: •••••@•••••