Study tests whether early surgery or watchful waiting is better for twin complications

NCT ID NCT01220011

Summary

This trial aimed to find the best approach for early-stage twin-twin transfusion syndrome (TTTS), a serious condition where twins share a placenta unevenly. It compared immediate laser surgery to careful weekly monitoring, with surgery only if the condition worsened. The goal was to see which approach led to better survival and brain health for babies by six months of age.

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Contacts and locations

Locations

  • Children's Hospital Colorado and Colorado Fetal Care Center

    Aurora, Colorado, 80045, United States

  • Fetal Care Center of Cincinnati, Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229-3026, United States

  • Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Fetal Therapy Program, Evergrenn Hospital Medical Center

    Kirkland, Washington, 98034, United States

  • Fetal Treatment Program of New England, Hasbro Children's Hospital, The Warren Alpert Medical School of Brown University.

    Providence, Rhode Island, 02903, United States

  • Hospital Ste-Justine

    Montreal, Quebec, H3T 1R2, Canada

  • Mount Sinai Hospital, University of Toronto

    Toronto, Ontario, ON M5X 1X5, Canada

  • Necker Enfants Malades

    Paris, 75006, France

  • The Ohio State University / OSU Fetal Therapy Program

    Columbus, Ohio, 43221, United States

  • The Texas Fetal Center, Children's Memorial Hermann Hospital, University of Texas Medical School

    Houston, Texas, 77030, United States

  • University of MD /Department of Obstetrics, Gynecology & Reproductive Sciences

    Baltimore, Maryland, 21000, United States

Conditions

Explore the condition pages connected to this study.