New drug could save infected artificial joints from removal

NCT ID NCT06621251

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 22 times

Summary

This study tests a drug called TRL1068 for people with a long-term infection in an artificial hip or knee joint. The goal is to see if the drug can clear the infection so the original joint can stay in place, avoiding the need for a major surgery to replace it. About 60 adults aged 18 to 85 with a first or repeat joint infection are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gulfcoast Research Institute

    Sarasota, Florida, 34232, United States

  • M3 Wake Research Associates

    Wilmington, North Carolina, 28412, United States

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224, United States

  • New England Baptist Hospital

    Boston, Massachusetts, 02120, United States

  • North Texas Medical Research Institute

    Rockwall, Texas, 75087, United States

  • OrthoArizona

    Gilbert, Arizona, 85234, United States

  • Phoenix Clinical Research

    Tamarac, Florida, 33321, United States

  • Sinai Hospital Baltimore

    Baltimore, Maryland, 21215, United States

  • UCLA

    Los Angeles, California, 90024, United States

  • University of Rochester

    Rochester, New York, 14623, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.