Triple threat: new vaccine aims to tackle three salmonella strains at once

NCT ID NCT05784701

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests a new vaccine designed to protect against three common types of Salmonella bacteria that cause serious infections in Sub-Saharan Africa. The trial includes healthy participants ranging from adults down to young infants, and compares the vaccine to a placebo to see if it is safe and triggers a strong immune response. Researchers are also testing different doses and a booster schedule to find the best way to use the vaccine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Trivalent Salmonella conjugate vaccine (TSCV)

What this could lead to

If successful, this vaccine could help protect against three major types of Salmonella infections, reducing severe illness and death in regions where these diseases are common.

What could go wrong

This is a Phase 2 trial, so the vaccine is still being tested for safety and immune response. It may not provide enough protection or could cause side effects, and larger studies are needed before it can be widely used.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

salmonellosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Vaccine Development (CVD-Mali)

    Bamako, Mali