New hope for rare nerve disease: phase 3 trial of nucresiran begins

NCT ID NCT07223203

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 26 times

Summary

This study tests a new medicine, nucresiran, for people with a rare inherited disease that damages nerves (hATTR-PN). About 125 adults will receive either nucresiran or another drug (vutrisiran) to see which better slows nerve damage and improves quality of life. The goal is to control the disease, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Trial Site

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Clinical Trial Site

    RECRUITING

    Boston, Massachusetts, 02118, United States

  • Clinical Trial Site

    RECRUITING

    Dallas, Texas, 75246, United States

  • Clinical Trial Site

    RECRUITING

    São Paulo, 04038-002, Brazil

  • Clinical Trial Site

    RECRUITING

    Le Kremlin-Bicêtre, 94270, France

  • Clinical Trial Site

    RECRUITING

    Florence, 50134, Italy

  • Clinical Trial Site

    RECRUITING

    Milan, 20133, Italy

  • Clinical Trial Site

    RECRUITING

    Suita, 565-0871, Japan

  • Clinical Trial Site

    RECRUITING

    Kuala Lumpur, 59100, Malaysia

  • Clinical Trial Site

    NOT_YET_RECRUITING

    Porto, 4099-001, Portugal

  • Clinical Trial Site

    RECRUITING

    Seoul, 05030, South Korea

  • Clinical Trial Site

    RECRUITING

    Seoul, 06351, South Korea

  • Clinical Trial Site

    RECRUITING

    Stockholm, 113 61, Sweden

  • Clinical Trial Site

    RECRUITING

    Umeå, 907 37, Sweden

  • Clinical Trial Site

    NOT_YET_RECRUITING

    Taipei, 112, Taiwan

  • Clinical Trial Site

    RECRUITING

    Taoyuan City, 333, Taiwan

Conditions

Explore the condition pages connected to this study.