Could a bone marrow shield boost lung cancer therapy?
NCT ID NCT03041311
First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 33 times
Summary
This study tested whether adding a drug called trilaciclib to standard chemotherapy and immunotherapy could protect the bone marrow and improve treatment effectiveness in 107 people with newly diagnosed extensive-stage small cell lung cancer. Participants received either trilaciclib or a placebo alongside their cancer drugs. The main goal was to see if trilaciclib reduced the length and occurrence of severe low white blood cell counts, a common side effect of chemotherapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beverly Hills Cancer Center
Beverly Hills, California, 90211, United States
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Blue Ridge Cancer Care
Blacksburg, Virginia, 24060, United States
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CHU Caen De La Côte De Nacre
Caen, 14033, France
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Centre Oscar Lambret
Lille, 59020, France
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Chernivtsi Regional Clinical Oncology Center
Chernivtsi, 58013, Ukraine
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Complex Oncology Center - Burgas
Burgas, 8000, Bulgaria
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Daugavpils Regional Hospital, Department of Oncology
Daugavpils, LV-5417, Latvia
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Dnipropetrovsk City Multispecialty Clinical Hospital #4
Dnipro, 49102, Ukraine
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East Tallinn Central Hospital Ltd., Clinic of Internal Medicine, Center for Oncology
Tallinn, 11312, Estonia
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Fort Belvoir Community Hospital
Fort Belvoir, Virginia, 22060, United States
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Gibbs Cancer Center
Spartanburg, South Carolina, 29303, United States
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H. Donostia, Hospital Donostia- Servicio de Oncología
San Sebastián, 20014, Spain
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H.U. Quirón Dexeus, Hospital Universitario
Barcelona, 08028, Spain
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Horizon Oncology Center
Lafayette, Indiana, 47905, United States
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Hospital 12 de Octubre
Madrid, 28041, Spain
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Hospital Arnau de Vilanova
Valencia, 46015, Spain
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Hospital Clinic de Barcelona- Servicio de Oncología Médica
Barcelona, 08036, Spain
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Hospital Clínico
San Carlos, Madrid, 28040, Spain
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Hospital Teresa Herrera
A Coruña, La Coruña, 15006, Spain
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Hospital Universitario Ntra. Sra. de Valme
Seville, 41014, Spain
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Hospital Universitario Puerta de Hierro Majadahonda
Majadahonda, Madrid, 28222, Spain
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Hospital Universitario Ramón y Cajal
Madrid, 28034, Spain
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Hospital Universitario Son Espases
Palma, Balearic Islands, 07120, Spain
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Joliet Oncology-Hematology Associates
Joliet, Illinois, 60435, United States
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Loma Linda University
Loma Linda, California, 92350, United States
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Lviv State Regional Treatment and Diagnostics Oncology Center
Lviv, 79031, Ukraine
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Millennium Oncology
Houston, Texas, 77090, United States
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Multiprofile Hospital for Active Treatment "Serdika"
Sofia, 1303, Bulgaria
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Multiprofile Hospital for Active Treatment "Serdika", Sofia
Sofia, 1303, Bulgaria
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Northern Westchester Hospital
Mount Kisco, New York, 10549, United States
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Northside Hospital - Georgia Cancer Specialists
Atlanta, Georgia, 30341, United States
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Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
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Oklahoma University - Peggy and Charles Stephenson Cancer Center
Oklahoma City, Oklahoma, 73117, United States
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Pauls Stradiņš Clinical University Hospital, Oncology Clinic
Riga, LV-1002, Latvia
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Piedmont Cancer Institute
Atlanta, Georgia, 30318, United States
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Redwood Regional Medical Group (RRMG) - Fountain Grove
Santa Rosa, California, 95403, United States
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Singing River Health System
Whittier, California, 90603, United States
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St. Jude Heritage Healthcare
Fullerton, California, 92835, United States
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St. Louis Cancer Care, LLP, North County
Bridgeton, Missouri, 63044, United States
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Summit Medical Group, P.A.
Morristown, New Jersey, 07962, United States
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The Alvin J. Siteman Cancer Center - Center for Advanced Med
St Louis, Missouri, 63110-1094, United States
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Trinity Health - Trinity CancerCare Center
Minot, North Dakota, 58701, United States
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UCLA Medical Center - Santa Monica Hematology And Oncology
Santa Monica, California, 90404, United States
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Valley Cancer Associates
Harlingen, Texas, 78550, United States
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Virginia Cancer Specialists
Arlington, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.