New oil may cut Life-Threatening events in kids with rare fat disorder

NCT ID NCT05933200

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 34 times

Summary

This study compares triheptanoin, a special oil, to standard MCT oil in 69 children (newborn to under 18) with long-chain fatty acid oxidation disorders (LC-FAOD), a rare condition where the body can't break down certain fats for energy. The goal is to see if triheptanoin reduces major clinical events like hospitalizations or hypoglycemia. Participants take the oil daily and are monitored for about a year.

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Contacts and locations

Locations

  • Cerrahpasa Medical Faculty

    Istanbul, 34116, Turkey (Türkiye)

  • Cukurova University

    Adana, Turkey (Türkiye)

  • Ege University

    Bornova-İzmir, Turkey (Türkiye)

  • Gazi University

    Ankara, Turkey (Türkiye)

  • Gdańksi Uniwersytet Medyczny

    Gdansk, Pomeranian Voivodeship, 80-952, Poland

  • General University Hospital in Prague-GUH (Všeobecná fakultní nemocnice v Praze- VFN)

    Prague, 120-08, Czechia

  • Instytut Pomnik-Centrum Zdrowia Dziecka

    Warsaw, Masovian Voivodeship, 04-730, Poland

  • Istanbul Universitesi Istanbul Tip Fakultesi Hastanesi

    Istanbul, 34093, Turkey (Türkiye)

  • Juntendo University Hospital

    Bunkyo City, Tokyo, 113-8431, Japan

  • King Faisal Specialist Hospital & Research Centre

    Riyadh, 11211, Saudi Arabia

  • Sant Joan de Deu Hospital (SJD)

    Barcelona, Esplugues de Llobregat, 08950, Spain

  • The Jikei University Hospital

    Minato, Tokyo, Japan

  • University Hospital 12 de Octubre

    Madrid, 28041, Spain

  • University Hospital Santiago de Compostela

    A Coruña, 15706, Spain

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, 79106, Germany

Conditions

Explore the condition pages connected to this study.