Dietary oil shows promise for rare muscle disorder
NCT ID NCT02919631
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a dietary oil called triheptanoin can improve exercise capacity in adults with McArdle disease, a rare genetic disorder that affects how muscles use stored sugar. Twelve participants received either triheptanoin or a placebo oil for two weeks, then switched after a washout period. Researchers measured heart rate during cycling and fatigue levels to see if the oil helped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Triheptanoin (a dietary oil)
- What this could lead to
- If it works, triheptanoin could improve exercise tolerance and reduce fatigue in people with McArdle disease.
- What could go wrong
- This is a small, early-phase trial with only 12 participants. Results may not apply to everyone, and the oil may not show meaningful benefit over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pitié-Salpêtrière,centre de référence de pathologie neuromusculaire, 47 Bd de l'hôpital
Paris, 75651, France