New heart valve clip could spare patients from Open-Heart surgery

NCT ID NCT07433504

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a new device that clips together the leaflets of a leaky tricuspid valve, aiming to fix it without open-heart surgery. It will enroll 132 people with severe tricuspid regurgitation who are already on standard medications. The study compares the clip plus medication to medication alone, tracking deaths, reoperations, hospital readmissions, and symptom improvement over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcatheter tricuspid valve clipping system

What this could lead to

If successful, this could offer a less invasive treatment option for people with severe tricuspid regurgitation, potentially reducing symptoms and hospital stays.

What could go wrong

This is an early-stage trial with only 132 participants, so results may not apply to everyone. The procedure carries risks like bleeding, infection, or device complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhongshan Hospital, Fudan University

    RECRUITING

    Shanghai, China